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In Vivo Animal Models

Scantox is highly experienced in generating, characterizing, and maintaining transgenic as well as induced disease animal models and using them for drug efficacy analyses for more than 20 years.

Animal models are indispensable tools to advance our understanding of the brain and nervous system. They offer unparalleled insights into the complex mechanisms that underlie neurological disorders and play a crucial role in the development of new treatments and therapies that can improve the lives of millions of people worldwide. Selecting the most appropriate model is a crucial step for successful research. We follow state-of-the-art methods to characterize all our models, to validate that they are properly mimicking the disease´s pathology and thus guaranteeing a high translational value. All models we offer are carefully selected, and already well-characterized in-house.

We offer several mouse and rat models for drug efficacy tests in Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), lysosomal storage disease (LSD), amyotrophic lateral sclerosis (ALS), autism spectrum disorder (ASD), schizophrenia, frontotemporal lobar degeneration (FTLD), and other neurodegenerative, mental, and rare diseases.

We are happy to receive your inquiry to elaborate the most efficient analysis options, including behavioralimmunohistochemicalbiochemical, and molecular biological techniques, to support your drug development project. Additionally, our biobank can provide various samples, such as brain tissue, CSF, and organs for analyses in your laboratory.

Is your preferred model not listed below? Contact us to discuss available alternatives!

histology services

Scantox offers a full set of histology services ranging from collection of tissue samples to delivering study reports that contain all experimental procedures and their outcome.
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Scantox Department of Translational Medicine offers a selection of molecular biological methods for the investigation of various diseases. The unit supports in vitro and in vivo studies performed at Scantox.
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In vitro Services

Scantox provides research services with numerous standardized cell culture systems including transgenic and non-transgenic cell lines, glial cells, primary chicken and rat peripheral and central nervous system neurons of different development stages and organotypic brain slices. New models are developed and validated on request.
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