The Pasta Gnawing Test is a stress-free behavioral test suitable for evaluation of motor deficits in rodents.
During the test, the rodents receive a dry spaghetti in their home cage and gnawing noises of the animals while eating are recorded. Parameters such as biting speed and number of bites per chewing episode are evaluated.
![Pasta-Gnawing-Test-Chart Pasta-Gnawing-Test-Chart](https://scantox.com/wp-content/uploads/2022/08/Pasta-Gnawing-Test-Chart.jpg)
![Pasta-Gnawing-Test Pasta-Gnawing-Test](https://scantox.com/wp-content/uploads/2022/08/Pasta-Gnawing-Test.jpg)
Evaluation of biting peaks in the pasta gnawing test in TAR6/6 transgenic mice. Biting peaks per episode of TDP-43 transgenic TAR6/6 male animals in the pasta gnawing test compared to ntg littermates. n = 10 – 15 per group; Two-way ANOVA with Bonferroni post hoc test; ***p<0.001. Sonogram with gnawing events:
![Pasta-Gnawing-sonogram1 sonogram](https://scantox.com/wp-content/uploads/2020/02/Pasta-Gnawing-sonogram1.png)
See wavesound file for auditory record!
See wavesound file for auditory record!
Line 61 tg (3 months)
Line 61 ntg (3 months)