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BlueScreen™ HC is a high-throughput gene reporter assay, developed by Scantox, which measures increased transcription of GADD45-alpha – a key event in the cellular response to genotoxic stress and damage.

Service infomation

BlueScreen™ HC utilises a luciferase reporter, offering a good signal-to-noise ratio.

The assay has the advantage of high sensitivity and high specificity compared with the in vitro regulatory battery assays, reducing the number of misleading positives early in compound development. The assay has been extensively validated across a wide range of applicability domains, demonstrating high utility and accuracy for the screening of genotoxic hazard.

Service

BlueScreen™ HC services are offered with rapid delivery of high specificity data with minimal compound consumption.  As the originators of these assays, Scantox has unique knowledge and expertise in the performance of these assays and data interpretation.

Notice: Gentronix Limited is a part of Scantox Group and these services are offered by Gentronix.