Publications

Barbara Hinteregger ^{1 2}, Tina Loeffler ¹, Stefanie Flunkert ¹, Joerg Neddens ¹, Thomas A Bayer ³, Tobias Madl ^{2 4}, Birgit Hutter-Paier ¹

1 – QPS Austria GmbH, Grambach, Austria.
2 – Gottfried Schatz Research Center (for Cell Signaling, Metabolism and Aging), Division of Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.
3 – Department of Psychiatry and Psychotherapy, Division of Molecular Psychiatry, University Medical Center, Göttingen (UMG), Göttingen, Germany.
4 – BioTechMed-Graz, Graz, Austria.

Agnes Molnar-Kasza ¹, Barbara Hinteregger ¹, Joerg Neddens ¹, Roland Rabl ¹, Stefanie Flunkert ¹, Birgit Hutter-Paier ¹

1 – QPS Austria GmbH, Grambach, Austria.

Thomas Filip ^{1 2}, Severin Mairinger ^{1 3,} Joerg Neddens ⁴, Michael Sauberer ^{1 5}, Stefanie Flunkert ⁴, Johann Stanek ^{1 5}, Thomas Wanek ^{1 5}, Nobuyuki Okamura ⁶, Oliver Langer ^{1 3 5,} Birgit Hutter-Paier ⁴, Claudia Kuntner ^{7 8}

1 – Preclinical Molecular Imaging, AIT Austrian Institute of Technology GmbH, 2444, Seibersdorf, Austria.
2 – Department of Biomedical Research, Medical University Vienna, Vienna, Austria.
3 – Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.
4 – Neuropharmacology, QPS Austria GmbH, Grambach, Austria.
5 – Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.
6 – Division of Pharmacology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
7 – Preclinical Molecular Imaging, AIT Austrian Institute of Technology GmbH, 2444, Seibersdorf, Austria. claudia.kuntner@meduniwien.ac.at.
8 – Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria. claudia.kuntner@meduniwien.ac.at.
#Contributed equally.

David Gate ^{1 2 3}, Emma Tapp ^{2 3,} Olivia Leventhal ^{2 3}, Marian Shahid ², Tim J Nonninger ^{2 3}, Andrew C Yang ^{4 5}, Katharina Strempfl ^{6 7 8}, Michael S Unger ^{6 7}, Tobias Fehlmann ⁹, Hamilton Oh ^{2 3}, Divya Channappa ², Victor W Henderson ², Andreas Keller ^{2 9}, Ludwig Aigner ^{6 7}, Douglas R Galasko ¹⁰, Mark M Davis ^{11 12}, Kathleen L Poston ², Tony Wyss-Coray ^{2 3 5}

1 – Department of Neurology, Northwestern University, Chicago, IL, USA.
2 – Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
3 – Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA.
4 – Department of Bioengineering, Stanford University, Stanford, CA, USA.
5 – Chemistry, Engineering, and Medicine for Human Health (ChEM-H), Stanford University, Stanford, CA, USA.
6 – Institute of Molecular Regenerative Medicine, Paracelsus Medical University, Salzburg, Austria.
7 – Spinal Cord Injury and Tissue Regeneration Center Salzburg, Paracelsus Medical University, Salzburg, Austria.
8 – QPS Austria GmbH, Parkring 12, 8074 Grambach, Austria.
9 – Chair for Clinical Bioinformatics, Saarland University, Saarbrucken, Germany.
10 – Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
11 – Department of Microbiology and Immunology, School of Medicine, Stanford University, Stanford, CA, USA.
12 – Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA.

Jackson A Roberts ^{1 2}, Vijay R Varma ¹, Yang An ³, Sudhir Varma ⁴, Julián Candia ^{5 6}, Giovanna Fantoni ⁷, Vinod Tiwari ⁸, Carlos Anerillas ⁹, Andrew Williamson ¹, Atsushi Saito ¹⁰, Tina Loeffler ¹¹, Irene Schilcher ¹¹, Ruin Moaddel ¹², Mohammed Khadeer ¹², Jacqueline Lovett ¹², Toshiko Tanaka ⁶, Olga Pletnikova ^{10 13}, Juan C Troncoso ^{10 14}, David A Bennett ¹⁵, Marilyn S Albert ¹⁴, Kaiwen Yu ¹⁶, Mingming Niu ¹⁶, Vahram Haroutunian ^{17 18}, Bin Zhang ¹⁹, Junmin Peng ¹⁶, Deborah L Croteau ⁸, Susan M Resnick ³, Myriam Gorospe ⁹, Vilhelm A Bohr ⁸, Luigi Ferrucci ⁶, Madhav Thambisetty ¹

1 – Clinical and Translational Neuroscience Section, Laboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
2 – Columbia University Vagelos College of Physicians and Surgeons, New York, NY 10032.
3 – Brain Aging and Behavior Section, Laboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
4 – HiThru Analytics, Laurel, MD 20707, USA.
5 – Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
6 – Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
7 – Clinical Research Core, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
8 – Section on DNA Repair, National Institute on Aging, Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA.
9 – Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
10 – Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
11 – QPS Austria GmbH, Parkring 12, 8074 Grambach, Austria.
12 – Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.
13 – Department of Pathology and Anatomical Sciences, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203, USA.
14 – Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
15 – Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, IL 60612, USA.
16 – Departments of Structural Biology and Developmental Neurobiology, Center for Proteomics and Metabolomics, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA.
17 – Departments of Psychiatry and Neuroscience, The Alzheimer’s Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
18 – Mental Illness Research, Education and Clinical Center (MIRECC), James J. Peters VA Medical Center, Bronx, NY 10468, USA.
19 – Department of Genetics and Genomic Sciences and Department of Pharmacological Sciences, Mount Sinai Center for Transformative Disease Modeling, Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Torsten Hoffmann ¹, Jens-Ulrich Rahfeld ², Mathias Schenk ², Falk Ponath ³, Koki Makioka ³, Birgit Hutter-Paier ⁴, Inge Lues ¹, Cynthia A Lemere ³, Stephan Schilling ^{2 5}

1 – Vivoryon Therapeutics N.V., Weinbergweg 22, 06120 Halle, Germany.
2 – Fraunhofer Institute for Cell Therapy and Immunology, Department of Drug Design and Target Validation, Weinbergweg 22, 06120 Halle, Germany.
3 – Department of Neurology, Brigham and Women’s Hospital, Harvard Medical School, 60 Fenwood Rd., Boston, MA 02115, USA.
4 – QPS Austria GmbH, Department of Neuropharmacology, Parkring 12, A-8074 Grambach, Austria.
5 – Anhalt University of Applied Sciences, Bernburger Straße 55, 06366 Köthen, Germany.

Kristina Dominko ¹, Ana Rastija ¹, Sandra Sobocanec ², Lea Vidatic ¹, Sarah Meglaj ³, Andrea Lovincic Babic ³, Birgit Hutter-Paier ⁴, Alessio-Vittorio Colombo ⁵, Stefan F Lichtenthaler ^{5 6 7}, Sabina Tahirovic ⁵, Silva Hecimovic ¹

1 – Laboratory for Neurodegenerative Disease Research, Division of Molecular Medicine, Ruder Boskovic Institute, 10000 Zagreb, Croatia.
2 – Laboratory for Mitochondrial Bioenergetics and Diabetes, Division of Molecular Medicine, Ruder Boskovic Institute, 10000 Zagreb, Croatia.
3 – Division of Biology, Faculty of Science, University of Zagreb, 10000 Zagreb, Croatia.
4 – QPS Austria GmbH, 8074 Grambach, Austria.
5 – German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany.
6 – Neuroproteomics, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, 81675 Munich, Germany.
7 – Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.

Katharina Strempfl ^{1 2 3}, Michael S Unger ^{1 2}, Stefanie Flunkert ³, Andrea Trost ⁴, Herbert A Reitsamer ⁴, Birgit Hutter-Paier ³, Ludwig Aigner 1 2

1 – Institute of Molecular Regenerative Medicine, Paracelsus Medical University, 5020 Salzburg, Austria.
2 – Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TReCS), Paracelsus Medical University, 5020 Salzburg, Austria.
3 – QPS Austria GmbH, Neuropharmacology, 8074 Grambach, Austria.
4 – University Clinic of Ophthalmology and Optometry, Research Program for Ophthalmology and Glaucoma Research, Paracelsus Medical University, 5020 Salzburg, Austria.

Rishi J Desai ¹, Mufaddal Mahesri ¹, Su Been Lee ¹, Vijay R Varma ², Tina Loeffler ³, Irene Schilcher ³, Tobias Gerhard ^{4 5}, Jodi B Segal ⁶, Mary E Ritchey ⁴, Daniel B Horton ^{4 7}, Seoyoung C Kim ^{1 8}, Sebastian Schneeweiss ¹, Madhav Thambisetty ²

1 – Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital & Harvard Medical School, Boston, MA 02115, USA.
2 – Clinical & Translational Neuroscience Section, Laboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, MD 21224, USA.
3 – QPS Austria GmbH, Parkring 12, 8074 Grambach, Austria.
4 – Rutgers Center for Pharmacoepidemiology and Treatment Science, New Brunswick, NJ 08901, USA.
5 – Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, USA.
6 – Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
7 – Rutgers Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ 08901, USA.
8 – Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA.

Vijay R Varma ¹, Rishi J Desai ², Sheeja Navakkode ^{3 4}, Lik-Wei Wong ^{4 5}, Carlos Anerillas ⁶, Tina Loeffler ⁷, Irene Schilcher ⁷, Mufaddal Mahesri ², Kristyn Chin ², Daniel B Horton ⁸, Seoyoung C Kim ², Tobias Gerhard ⁸, Jodi B Segal ⁹, Sebastian Schneeweiss ², Myriam Gorospe ⁶, Sreedharan Sajikumar ^{4 5 10}, Madhav Thambisetty ¹¹

1 – Clinical and Translational Neuroscience Section, Laboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, MD, USA.
2 – Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA.
3 – Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
4 – Department of Physiology, National University of Singapore, Singapore, Singapore.
5 – Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
6 – Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA.
7 – QPS Austria GmbH, Parkring 12, 8074, Grambach, Austria.
8 – Center for Pharmacoepidemiology and Treatment Science, Ernest Mario School of Pharmacy, Rutgers University, New Brunswick, NJ, USA.
9 – Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
10 – Life Sciences Institute Neurobiology Programme, National University of Singapore, Singapore, Singapore.
11 – Clinical and Translational Neuroscience Section, Laboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, MD, USA. thambisettym@mail.nih.gov.

Shirin Sharghi ^{1 2}, Stefanie Flunkert ¹, Magdalena Daurer ¹, Roland Rabl ¹, Boris Philippe Chagnaud ², Marcello Leopoldo ³, Enza Lacivita ³, Birgit Hutter-Paier ¹, Manuela Prokesch ¹

1 – Department of Neuropharmacology, QPS Austria GmbH, Grambach, Austria.
2 – Institute for Biology, Karl-Franzens-Universität Graz, Graz, Austria.
3 – Department of Pharmacy-Drug Sciences, University of Bari Aldo Moro, Bari, Italy.

Joshua Adekunle Babalola ¹, Magdalena Lang ², Meekha George ³, Anika Stracke ², Carmen Tam-Amersdorfer ², Izaskun Itxaso ⁴, Domjan Lucija ⁴, Jelena Tadic ⁵, Irene Schilcher ⁴, Tina Loeffler ⁴, Stefanie Flunkert ⁴, Manuela Prokesch ⁴, Gerd Leitinger ⁶, Achim Lass ⁵, Birgit Hutter-Paier ⁴, Ute Panzenboeck ², Gerald Hoefler ⁷

1 – Diagnostic and Research Institute of Pathology, Medical University of Graz, Austria.
2 – Otto Loewi Research Center, Division of Immunology, Medical University of Graz, Austria.
3 – Department of Obstetrics and Gynaecology, Medical University of Graz, Austria.
4 – QPS Austria GmbH, Grambach, Austria.
5 – Institute of Molecular Biosciences, University of Graz, Austria.
6 – Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Austria.
7 – Diagnostic and Research Institute of Pathology, Medical University of Graz, Austria. Electronic address: Gerald.Hoefler@uniklinikum.kages.at.

Joshua Adekunle Babalola ¹, Anika Stracke ², Tina Loeffler ³, Irene Schilcher ³, Sideromenos Spyridon ⁴, Stefanie Flunkert ³, Joerg Neddens ³, Ake Lignell ⁵, Manuela Prokesch ³, Ute Pazenboeck ², Herbert Strobl ², Jelena Tadic ⁶, Gerd Leitinger ⁷, Achim Lass ⁶, Birgit Hutter-Paier ³, Gerald Hoefler ⁸

1 – Diagnostic and Research Institute of Pathology Medical University of Graz, Graz, Austria.
2 – Division of Immunology and Pathophysiology, Otto Loewi Research Center, Medical University of Graz, Austria.
3 – QPS Austria GmbH, Grambach, Austria.
4 – QPS Austria GmbH, Grambach, Austria; Medical University of Vienna, Vienna, Austria.
5 – AstaReal AB, Sweden.
6 – Institute of Molecular Biosciences, University of Graz, Austria.
7 – Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Austria.
8 – Diagnostic and Research Institute of Pathology Medical University of Graz, Graz, Austria. Electronic address: gerald.hoefler@medunigraz.at.

Frederik Rode ¹ ,Christoffer Bundgaard ² , Johan Areberg ² , Lone Bruhn Madsen ³ , Ida Taavoniku ³ , Lene Hansen ² , Johan Weisser ² , Line Rørbæk Olsen ² , Heidi Toft Elgaard ² , Elin Eneberg ² , Michael Didriksen ²

• ¹ H. Lundbeck, Copenhagen, Denmark.
• ² H. Lundbeck, Copenhagen, Denmark.
• ³ Scantox Sweden, Lund, Sweden.

Andreas Bråve ^{a b}, Lindvi Gudmundsdotter ^{a b}, Eric Sandström ^c, B. Kristian Haller ^d, David Hallengärd ^{a b}, Anna-Karin Maltais ^e, Alan D. King ^f, Richard R. Stout ^g, Pontus Blomberg ^h, Urban Höglund ⁱ, Bo Hejdeman ^c, Gunnel Biberfeld ^a, Britta Wahren ^{a b}

a – Swedish Institute for Infectious Disease Control, Solna, Sweden
b – Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden
c- Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden
d – Department of Oncology and Pathology, Cancer Center Karolinska, Karolinska Institutet, Stockholm, Sweden
e – Cyto Pulse Sciences Inc., Solna, Sweden
f – Cellectis Bioresearch, Inc., Glen Burnie MD, USA
g – Bioject Medical Technologies, Tualatin, OR, USA
h – Vecura, Karolinska University Hospital, Huddinge, Sweden
i – Visionar Preclinical AB, Uppsala, Sweden

Peter Glerup, Nanna Grand, Mikala Skydsgaard

Scantox A/S, Lille Skensved, Denmark

V. Golozoubova, T.K. Brodersen, S. Klastrup, M. Oksama, J. Løgsted, A. Makin

Scantox A/S, Lille Skensved, Denmark

A. Makin, Sisse Ellemann-Laursen, Nanna Grand, Gitte Jeppesen, T. Starostka, J. Løgsted, K. Kaaber

Wojciech Senkowski; Xiaonan Zhang; Maria Hägg Olofsson; Ruben Isacson; Urban Höglund; Mats Gustafsson; Peter Nygren; Stig Linder; Rolf Larsson; Mårten Fryknäs

Uppsala University, Klinisk Farmakologi, ing 61 4tr, Dag Hammarskjölds Väg 18, 751 85 Uppsala, Sweden

Michael Karlsson ^{a b 1}, Johannes K. Ehinger ^{a b 1}, Sarah Piel ^{a b}, Fredrik Sjövall ^a, Johanna Henriksnäs ^c, Urban Höglund ^c, Magnus J. Hansson ^{a b}, Eskil Elmér ^{a b}

a – Mitochondrial Medicine, Department of Clinical Sciences, Lund University, BMC A13, SE-221 84 Lund, Sweden
b – NeuroVive Pharmaceutical AB, Medicon Village, Scheelevägen 2, SE-233 81 Lund, Sweden
c – Scantox Solna (Adlego Biomedical AB), P.O. Box 42, SE-751 03 Uppsala, Sweden

Gustaf Ahlén; Jonas Söderholm; Torunn Tjelle; Rune Kjeken; Lars Frelin; Urban Höglund; Pontus Blomberg; Michael Fons; Iacob Mathiesen; Matti Sällberg

Division of Clinical Microbiology, F68, Karolinska Institutet at Karolinska University Hospital, Huddinge, Stockholm, Sweden

Pham-Tue-Hung Tran¹, Naveed Asghar¹, Urban Höglund², Olivia Larsson², Lars Haag³, Ali Mirazimi^4,5, Magnus Johansson¹, Wessam Melik¹

¹ – School of Medical Science, Inflammatory Response and Infection Susceptibility Centre (iRiSC), Örebro University, 703 62 Örebro, Sweden
² – Scantox Solna (Adlego Biomedical AB), P.O. Box 42, 751 03 Uppsala, Sweden
³ – EM Unit (EMil), Department of Laboratory Medicine, Karolinska Institute, 171 77 Solna, Sweden
⁴ – Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, 141 52 Huddinge, Sweden
⁵ – National Veterinary Institute, 751 89 Uppsala, Sweden

Madalene Å Andersson¹, Lone Bruhn Madsen², Artur Schmidtchen ^3,4,5, Manoj Puthia⁵

¹ – In2Cure AB, Medicon Village, SE-22381 Lund, Sweden.
² – Scantox Lund (Timeline Bioresearch), Medicon Village, SE-22363 Lund, Sweden.
³ – Copenhagen Wound Healing Center, Bispebjerg Hospital, Department of Biomedical Sciences, University of Copenhagen, DK-2400 Copenhagen, Denmark.
⁴ – Dermatology, Skåne University Hospital, SE-22185 Lund, Sweden.
⁵ – Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, SE-22184 Lund, Sweden.

Enamul Haque Mojumdar ^{1, 2}, Lone Bruhn Madsen³, Henri Hansson⁴, Ida Taavoniku³, Klaus Kristensen³, Christina Persson⁵, Anna Karin Morén⁴, Rajmund Mokso⁶, Artur Schmidtchen⁷, Tautgirdas Ruzgas^{1, 2}, Johan Engblom^{1, 2}

¹ – Department of Biomedical Science, Faculty of Health and Society, Malmö University, SE-205 06 Malmö, Sweden.
² – Biofilms-Research Center for Biointerfaces (BRCB), Malmö University, SE-205 06 Malmö, Sweden.
³ – Scantox Lund (Timeline Bioresearch AB), Scheelevägen 2, SE-223 63 Lund, Sweden.
⁴ – Galenica AB, Medeon Science Park, SE-205 12 Malmö, Sweden.
⁵ – Department of Occupational and Environmental Dermatology, Lund University, Skåne University Hospital, SE-205 02 Malmö, Sweden.
⁶ – Department of Solid Mechanics & MAX IV Laboratory, Lund University, SE-221 00 Lund, Sweden.
⁷ – Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, SE-221 84 Lund, Sweden.
8 – Copenhagen Wound Healing Center, Bispebjerg Hospital, Department of Biomedical Sciences, University of Copenhagen, DK-2400 Copenhagen, Denmark.

Sandra Edwards, Nanna Grand

Pham-Tue-Hung Tran¹, Urban Höglund², Olivia Larsson², Sofia Appelberg³, Ali Murazimi^4,5, Magnus Johansson¹, Wessam Melin¹

¹ – School of Medical Science, Inflammatory Response and Infection Susceptibility Centre (iRiSC), Örebro University, 703 62 Örebro, Sweden
² – Scantox Solna (Adlego Biomedical AB), P.O. Box 42, 751 03 Uppsala, Sweden
³ – Department of Microbiology, Public Health Agency of Sweden, 171 82 Solna, Sweden
⁴ – Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institution, 141 52 Huddinge, Sweden
⁵ – National Veterinary Institute, 751 89 Uppsala, Sweden

Rüdiger Groß¹, Lívia Mesquita Dias Loiola^2,3, Leila Issmail⁴, Nadja Uhlig⁴, Valentina Eberlein⁴, Carina Conzelmann¹, Lia‐Raluca Olari¹, Lena Rauch¹, Jan Lawrenz¹, Tatjana Weil¹, Janis A. Müller¹, Mateus Borba Cardoso³, Andrea Gilg¹, Olivia Larsson⁵, Urban Höglund⁵, Sandra Axberg Pålsson⁶, Anna Selch Tvilum², Kaja Borup Løvschall², Maria M. Kristensen², Anna‐Lena Spetz⁶, Fortune Hontonnou⁷, Marie Galloux⁷, Thomas Grunwald⁴, Alexander N. Zelikin², Jan Münch¹

¹ – Institute of Molecular Virology, Ulm University Medical Center, Ulm 89081 Germany
² – Department of Chemistry and iNano Interdisciplinary Nanoscience Centre, Aarhus University, Aarhus 8000 Denmark
³ – Brazilian Synchrotron Light Laboratory, Brazilian Center for Research in Energy and Materials, Campinas São Paulo, 13083‐970 Brazil
⁴ – Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig 04103 Germany
⁵ – Scantox Solna (Adlego Biomedical AB), Solna 171 65 Sweden
⁶ – Department of Molecular Biosciences, The Wenner‐Gren Institute Stockholm University, Stockholm 10691 Sweden
⁷ – Université Paris‐Saclay, INRAE, UVSQ, VIM, Jouy‐en‐Josas 78352 France

Sofia Appelberg ¹, Gustaf Ahlén², Jingyi Yan², Negin Nikouyan², Sofie Weber³, Olivia Larsson³, Urban Höglund³, Soo Aleman⁴, Friedemann Weber⁵, Emma Perlhamre⁶, Johanna Apro⁶, Eva‐Karin Gidlund⁷, Ola Tuvesson⁷, Simona Salati⁸, Matteo Cadossi⁸, Hanna Tegel⁹, Sophia Hober⁹, Lars Frelin², Ali Mirazimi1, and Matti Sällberg²

1 – Public Health Agency of Sweden Solna Sweden
² – Department of Laboratory Medicine Karolinska Institutet Huddinge Sweden
³ – Scantox Solna (Adlego AB) Uppsala Sweden
⁴ – Department of Infectious Disease Karolinska University Hospital Huddinge Sweden
⁵ – Institute for Virology, FB10‐Veterinary Medicine, Justus‐Liebing University Giessen Giessen Germany
⁶ – Karolinska Trial Alliance Karolinska University Hospital Huddinge Sweden
⁷ – NorthX Biologics Matfors Sweden
⁸ – IGEA Bomedical Spa Carpi Italy
⁹ – Department of Protein Science Royal Institute of Technology Stockholm Sweden

Pham-Tue-Hung Tran¹, Naveed Asghar¹, Urban Höglund², Olivia Larsson², Lars Haag³, Ali Mirazimim^4,5, Magnus Johansson¹, Wessam Melik¹

¹ – School of Medical Science, Inflammatory Response and Infection Susceptibility Centre (iRiSC), Örebro University, 703 62 Örebro, Sweden
² – Scantox Solna (Adlego Biomedical AB), P.O. Box 42, 751 03 Uppsala, Sweden
³ – EM Unit (EMil), Department of Laboratory Medicine, Karolinska Institute, 171 77 Solna, Sweden
⁴ – Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, 141 52 Huddinge, Sweden
⁵ – National Veterinary Institute, 751 89 Uppsala, Sweden

Wael Bahnan¹, Sebastian Wrighton¹, Martin Sundwall¹, Anna Läckberg¹,², Olivia Larsson³, Urban Höglund³, Hamed Khakzad⁴,⁵, Magdalena Godzwon⁶, Maria Walle⁶, Elisabeth Elder⁷, Anna Söderlund Strand⁸, Lotta Happonen¹, Oscar André¹, Johannes Kumra Ahnlide¹, Thoms Hellmark⁹, Vidar Wendel-Hansen¹⁰, Robert P.A. Wallin¹¹, Johan Malmström¹, Lars Malmström¹,12, Mats Ohlin⁶,¹³, Magnus Rasmussen¹,², Pontus Nordenfelt¹

1 – Department of Clinical Sciences Lund, Infection Medicine, Faculty of Medicine, Lund University, Lund, Sweden
² – Infectious Disease Clinic, Skåne University Hospital, Lund, Sweden
³ – Scantox Solna (Adlego Biomedical AB), Uppsala, Sweden
⁴ – Equipe Signalisation Calcique et Infections Microbiennes, Ecole Normale Supérieure Paris-Saclay, Gif-sur-Yvette, France
⁵ – Institut National de la Santé et de la Recherche Médicale (INSERM) U1282, Gif-sur-Yvette, France
⁶ – Department of Immunotechnology, Lund University, Lund, Sweden
⁷ – Public Health Agency of Sweden, Solna, Sweden
⁸ – Department of Laboratory Medicine, Clinical Microbiology, Skane University Hospital Lund, Lund University, Lund, Sweden
⁹ – Department of Clinical Sciences Lund, Nephrology, Skane University Hospital Lund, Lund University, Lund, Sweden
¹⁰ – Tanea Medical Ab, Uppsala, Sweden
¹¹ – SciEd Solutions, Stockholm, Sweden
¹² – Institute for Computational Science, Zurich, Switzerland
¹³ – SciLifeLab Drug Discovery and Development, Lund University, Lund, Sweden

Vivi FH Jensen DVM PhD¹, Nikolai K Jensen DVM¹, Line H Schefe PhD¹, Jens Sigh PhD¹, Akiyemi Akintomide MSc², Kari Kaaber DVM³, Sophia G Moesgaard DVM PhD⁴, Mona H Pedersen PhD¹

¹ – Global Drug Discovery and Development Sciences, Novo Nordisk A/S, Maaloev, Denmark
² – Labcorp Early Development Laboratories Limited, Huntingdon, UK
³ – Scantox A/S, Lille Skensved, Denmark
⁴ – Y-mAbs Therapeutics A/S, Hørsholm, Denmark

Karin M Gilljam PhD, Patrik Stenlund PhD, Simon Standort MSc, Sisse Bindslev Andersen DVM,
Kari Kaaber DVM, Henrik Lund MD PhD, Karl R K Bryn MD

Arman Izadi¹, Arsema Hailu¹, Magdalena Godwon², Sebastian Wrighton¹, Berit Olofsson¹, Tobias Schmidt^3,4, Anna Söderlund-Strand⁵, Elizabeth Elder⁶, Sofia Appelberg⁷, Maria Valsjö⁸, Olivia Larsson⁸, Vidar Wendel-Hansen9, Mats Ohlin^2,10, Wael Bahnan¹, Pontus Nordenfelt¹,⁵.

¹ – Department of Clinical Sciences Lund, Division of Infection Medicine, Faculty of Medicine, Lund University, 221 84 Lund, Sweden.
² – Department of Immunotechnology, Faculty of Engineering, Lund University, 221 00 Lund, Sweden.
³ – Department of Clinical Sciences Lund, Division of Pediatrics, Faculty of Medicine, Lund University, 221 84 Lund, Sweden.
⁴ – Wallenberg Center for Molecular Medicine, Faculty of Medicine, Lund University, 221 84 Lund, Sweden.
⁵ – Department of Laboratory Medicine, Clinical Microbiology, Skåne University Hospital Lund, Lund University, 221 85 Lund, Sweden.
⁶ – Department of Microbiology, National Veterinary Institute, 751 89 Uppsala, Sweden.
⁷ – Department of Microbiology, Public Health Agency of Sweden, 171 82 Stockholm, Sweden.
⁸ – Scantox A/S, 171 65 Stockholm, Sweden.
⁹ – Tanea Medical AB, 751 83 Uppsala, Sweden.
¹⁰ – SciLifeLab Drug Discovery and Development, Lund University, 221 00 Lund, Sweden.

Torkel Falkenberg, Olivia Larsson, Bengt Hedin, Shigeru Shiraki, Takahisa Karita

Hina Jhelum, Nanna Grand, Kirsten Rosenmay Jacobsen, Sabrina Halecker, Michelle Salerno, Robert Prate, Luise Krüger, Yannick Kristiansen, Ludwig Krabben, Lars Möller, Michael Laue, Benedikt Kaufer, Kari Kaaber, Joachim Denner

Laboratory of Joachim Denner at the Robert Koch Institute and the Institute of Virology was supported by the Deutsche Forschungsgemeinschaft, TRR127.

Paulina Dabrowska-Schlepp¹, Andreas Busch¹, Jin-Song Shen², Rachel Y. Cheong³, Lone Bruhn Madsen³,
Daniel Mascher⁴, Raphael Schiffmann², Andreas Schlaaf¹

¹ – Eleva GmbH, Freiburg, Germany
² – Institute of Metabolic Disease, Baylor, Scott & White Research Institute, Dallas, Texas, USA
³ – Scantox Sweden (Previously Timeline Bioresearch AB), Lund, Sweden
⁴ – pharm-analyt Labor GmbH, Baden, Austria