Scientific Posters
Scantox encourages its scientists to publish and disseminate the results of their high quality research which is mostly done in close collaboration with our clients.
| Title | Year | Scantox Business Unit | Disease | Model | Keywords | Authors | Affiliations | Presented at | More details | hf:tax:division | hf:tax:disease | hf:tax:model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Demyelination in a 3D CNS Environment Insights from Organotypic Cerebellar Slices | 2025 | Discovery | Multiple Sclerosis | Organotypic Cerebellar Slices | Myelin, NF-L, Confocal imaging | Stefanie Krassnig, Irene Schilcher, Tina Loeffler, Irantzu Perez Ruiz, Magdalena Daurer, Stefanie Flunkert, Manuela Prokesch | Scantox Neuro GmbH, Grambach, Austria | SfN Neuroscience 2025, San Diego | scantox.com/wp-content/uploads/2025/11/Scantox-Poster-Demyelination-in-a-3D-CNS-Environment-Insights-from-Organotypic-Cerebellar-Slices.pdf | discovery | multiple-sclerosis | organotypic-cerebellar-slices |
| Unraveling the Complexity of Rotenone-Induced Parkinson’s Disease in Mice: Longitudinal Evaluation of Disease Pathology | 2025 | Discovery | Parkinson's disease | Rotenone-induced mice | Motor deficits, Neuronal loss, Neuroinflammation, Astrocytosis, Activated microglia, Dopamine dysfunction, Caudate putamen, Substantia nigra | Jauregi P.1,2, Rabl R.1, Daurer M.1, Breznik L.1, Flunkert S.1, Chagnaud B.2, Prokesch M.1
| 1Scantox Neuro GmbH, Grambach, Austria; | AD/PD 2025, Vienna | scantox.com/wp-content/uploads/2025/07/Scantox-Poster-Unraveling-the-Complexity-of-Rotenone-Induced-PD-in-Mice-Apr.2025.pdf | discovery | parkinsons-disease | rotenone-induced-mice |
| Accelerating Senescence in D-Galactose-Treated Mice | 2025 | Discovery | Aging | D-galactose induced mice | Aging, Motor performance, Cognition, beta-galactosidase activity, Wild type mice | Sharghi S., Breznik L., Daurer M., Loeffler T., Fantina-Woblistin A., Flunkert S., Prokesch M. | Scantox Neuro GmbH, Grambach, Austria | AD/PD 2025, Vienna | scantox.com/wp-content/uploads/2025/07/Scantox-Poster-Accelerating-Senescence-in-D-Galactose-Treated-Mice-Apr.2025.pdf | discovery | aging | d-galactose-induced-mice |
| Accelerating the Parkinson's Disease Phenotype in Line 61 Mice With D-Galactose | 2025 | Discovery | Parkinson's disease | Line 61 mice | Aging, Motor performance, Cognition, beta-galactosidase activity, MDA | Rabl R., Breznik L., Daurer M., Loeffler T., Fantina-Woblistin A., Flunkert S., Prokesch M. | Scantox Neuro GmbH, Grambach, Austria | AD/PD 2025, Vienna | scantox.com/wp-content/uploads/2025/07/Scantox-Poster-Accelerating-the-Parkinsons-Disease-Phenotype-in-Line-61-Mice-With-D-Galactose-Apr.2025.pdf | discovery | parkinsons-disease | line-61-mice |
| Compound Muscle Action Potential as a Translational Biomarker in Mouse Models of Parkinson's Disease | 2025 | Discovery | Parkinson's disease | A53T-alpha-synuclein | CMAP, Electromyography, hA53Ttg mice, | Breznik L., Daurer M., Fantina-Woblistin A., Rabl R., Flunkert S., Prokesch M. | Scantox Neuro GmbH, Grambach, Austria | AD/PD 2025, Vienna | scantox.com/wp-content/uploads/2025/07/Scantox-Poster-Compound-Muscle-Action-Potential-as-Translational-Biomarker-in-Mice-Apr.2025.pdf | discovery | parkinsons-disease | a53t-alpha-synuclein |
| Impact of SNCA A53T and GBA Gene Mutations on Neurite Outgrowth and Response to Parkinson's Disease Stressors in IPSC-Derived Neurons | 2025 | Discovery | Parkinson's disease | A53T-alpha-synuclein, iPSCs | Cell viability, MPP+, Rotenone, Mitochondrial activity, GCase activity | Perez-Ruiz I.1, Loeffler T.1, OosterveenT.2, Turner A.2, Daurer M.1, Breznik L.1, Flunkert S.1, Prokesch M.1 | 1Scantox Neuro GmbH, Grambach, Austria; | AD/PD 2025, Vienna | scantox.com/wp-content/uploads/2025/07/Scantox-Poster-Impact-of-SNCA-A53T-and-GBA-Gene-Mutations-on-Neurite-Outgrow-and-Response-Apr.2025.pdf | discovery | parkinsons-disease | a53t-alpha-synuclein ipscs |
| Method for Evaluation of Placental Transfer in Embryofetal Developmental Studies in Göttingen Minipigs at Scantox | 2025 | Regulatory Toxicology | n/a | Göttingen Minipig | Embryofetal development study; Göttingen Minipig | Sisse Ellemann-Laursen, Nanna Grand | Scantox A/S, Hestehavevej 36A, 4623 Lille Skensved, Denmark | ETS Repro 2025, Manchester | scantox.com/wp-content/uploads/2025/10/Scantox-Poster-Method-for-evaluation-of-placental-transfer-in-embryofetal-development.pdf | regulatory-toxicology | n-a | gottingen-minipig |
| Validation of Immunofluorescent Anti-Kinetochore (CREST) Staining in Rat Bone Marrow as part of the in vivo Micronucleus assay | 2025 | Genetic Toxicology | n/a | Han Wistar rat | Genetic toxicology; mammalian erythrocyte micronucleus test; micronucleus; Comet assay; immunofluorescent anti-kinetochore (CREST) staining; centromeres; chromosomes; fluorochrome-conjugated anti-human IgG antibody; bone marrow; Han Wistar rats | Fahima Begum, Julie Hayes | Gentronix Ltd | UKEMS 2025, York | scantox.com/wp-content/uploads/2025/11/UKEMS-Kinetochore-Labelling-Poster_Fahima-Begum.pdf | genetic-toxicology | n-a | han-wistar-rat |
| The in-vivo Comet Assay: Considerations for Validation of Optimal Study Design in a Regulatory Setting | 2025 | Genetic Toxicology | n/a | Han Wistar rat | in vivo alkaline comet assay; DNA strand breaks; electrophoresis; mouse lymphoma L5178Y cells; experimental design; Han Wistar rats | Teresa Chirom, Julie Hayes, Lucinda Lillford | Gentronix Ltd | EEMGS 2025, Bratislava | scantox.com/wp-content/uploads/2025/11/A0-Poster-EEMGS-2025_Scantox.pdf | genetic-toxicology | n-a | han-wistar-rat |
| Evaluation of Historical Control Liver and Duodenum Data from the Big Blue® TGR Assay - Is Sampling Day a Variant of Concern? | 2025 | Genetic Toxicology | n/a | Big Blue® Transgenic Rats | OECD 488; mutant frequency; liver; duodenum; germ cells | Karen Philp, Matt Tate | Gentronix Ltd | EMGS 2025, Rochester | scantox.com/wp-content/uploads/2025/11/EMGS-2025-TGR-HCD-poster_Aug25-1.pdf | genetic-toxicology | n-a | big-blue-transgenic-rats |
| Accelerated Aging in Cerebral Organoids | 2025 | Discovery | Alzheimer's disease | Cerebral Organoids | Human iPSCs, D-galactose, NFL, PAX6, GFAP, SNAP25, p53, p21, Senescence, NeuN, Astrocytosis, Synapses | Perez-Ruiz I., Loeffler T., Itxaso I., Daurer M., Breznik L., Flunkert S., Prokesch M. | Scantox Neuro GmbH, Grambach, Austria | AD/PD 2025, Vienna | scantox.com/wp-content/uploads/2025/07/Scantox-Poster-Accelerated-Aging-in-Cerebral-Organoids-Apr.2025-1.pdf | discovery | alzheimers-disease | cerebral-organoids |
| AAV-Human A53T-Mutated Synuclein Disrupts Nigro-Striatal System in Mice | 2025 | Discovery | Parkinson's disease | A53T-alpha-synuclein | Human α-synuclein, Tyrosine hydroxylase, Dopamine transporter, Activated microglia, T-cells, Mitochondrial markers | Ewald Auer, Tina Loeffler, Magdalena Daurer, Livia Breznik, Joerg Neddens, Stefanie Flunkert, Manuela Prokesch | Scantox Neuro GmbH, Grambach, Austria | SfN Neuroscience 2024, Chicago | scantox.com/wp-content/uploads/2025/11/Scantox-Poster-AAV-Human-A53T-Mutated-Synuclein-Disrupts-Nigro-Striatal-System-in-Mice.pdf | discovery | parkinsons-disease | a53t-alpha-synuclein |
| Characterization of a Yohimbine-Induced Rat Anxiety Model | 2025 | Discovery | Anxiety Disorder | Other | Open field test, Elevated plus maze, Prepulse inhibition, | Mateusz Dudek, Aaron Fantina-Woblistin, Laurenz Jauk, Roland Rabl, Livia Breznik, Magdalena Daurer, Irene Schilcher, Tina Loeffler, | Scantox Neuro GmbH, Grambach, Austria | SfN Neuroscience 2025, San Diego | scantox.com/wp-content/uploads/2025/11/Scantox-Poster-Characterization-of-a-Yohimbine-Induced-Rat-Anxiety-Model.pdf | discovery | anxiety-disorder | other |
| Characterization of an Inducible Intrathecal TDP43-AAV Amyotrophic Lateral Sclerosis Model | 2025 | Discovery | Amyotrophic lateral sclerosis | TAR6/6 mice | TDP-43, Open field test, Beam walk test, Wire hanging test, Clasping, NF-L | Roland Rabl, Benedikt Kien, Livia Breznik, Magdalena Daurer, Laurenz Jauk, Maja Ljekaj, Karin Plattner, Aaron Fantina-Woblistin, Tina Löffler, Stefan Ebner-Benke, Manuela Prokesch | Scantox Neuro GmbH, Grambach, Austria | SfN Neuroscience 2025, San Diego | scantox.com/wp-content/uploads/2025/11/Scantox-Poster-Characterization-of-an-Inducible-Intrathecal-TDP43-AAV-Amyotrophic-Lateral-Sclerosis-Model.pdf | discovery | amyotrophic-lateral-sclerosis | tar6-6-mice |
| Characterization of Second-Hit Mouse Models for Amyotrophic Lateral Sclerosis and Parkinson’s Disease Using Plasma Neurofilament-Light Chain as a Biomarker | 2025 | Discovery | Amyotrophic lateral sclerosis, Parkinson's disease | TAR6/6 mice | M83 α-Synuclein Seeding Model, Inducible Intrathecal TDP43-AAV Model, NF-L, mRNA Expression | Ewald Auer, Roland Rabl, Livia Breznik, Irene Schilcher, Tina Loeffler, Karin Plattner, Maja Ljekaj, Magdalena Daurer, Manuela Prokesch | Scantox Neuro GmbH, Grambach, Austria | SfN Neuroscience 2025, San Diego | scantox.com/wp-content/uploads/2025/11/Scantox-Poster-Characterization-of-Second-Hit-Mouse-Models-for-ALS-and-PD-Using-Plasma-NF-L-as-a-Biomarker.pdf | discovery | amyotrophic-lateral-sclerosis parkinsons-disease | tar6-6-mice |
| Chemotherapy-Induced Mitochondrial Dysfunction and Neuronal Damage in iPSC-Derived Sensory Neurons | 2025 | Discovery | Chemotherapy-induced peripheral neuropathy | iPSCs | Paclitaxel, Oxaliplatin, iPSC-derived sensory neurons | Irene Schilcher, Stefanie Krassnig, Tina Loeffler, Irantzu Perez Ruiz, Magdalena Daurer, Anja Zdouc, Manuela Prokesch | Scantox Neuro GmbH, Grambach, Austria | SfN Neuroscience 2025, San Diego | scantox.com/wp-content/uploads/2025/11/Scantox-Poster-Chemotherapy-Induced-Mitochondrial-Dysfunction-and-Neuronal-Damage-in-iPSC-Derived-Sensory-Neurons.pdf | discovery | chemotherapy-induced-peripheral-neuropathy | ipscs |
| 3D Neural Spheroids – A Platform for Neurodegenerative Diseases Modeling | 2025 | Discovery | Alzheimer's disease, Parkinson's disease | Neurospheres | 3D neural culture systems, NF-L, GFAP, Mitochondrial and neuronal activity | Stefanie Krassnig, Mirjam Pennauer, Irene Schilcher, Tina Loeffler, Irantzu Perez Ruiz, Stefanie Flunkert, Manuela Prokesch | Scantox Neuro GmbH, Grambach, Austria | SfN Neuroscience 2025, San Diego | scantox.com/wp-content/uploads/2025/11/Scantox-Poster-3D-Neural-Spheroids-%E2%80%93-A-Platform-for-Neurodegenerative-Diseases-Modeling.pdf | discovery | alzheimers-disease parkinsons-disease | neurospheres |
| Translational Neuroinflammation Assays for High-Throughput In Vitro Screening | 2025 | Discovery | Neuroinflammation | Cell line | Microglial cells, Lipopolysaccharide (LPS), Cytokine secretion, Cytokine mRNA expression | Krassnig S., Loecker A., Loeffler T., Schilcher I., Perez Ruiz I., Flunkert S., Prokesch M. | Scantox Neuro GmbH, Grambach, Austria | scantox.com/wp-content/uploads/2025/12/Scantox_Poster-Translational-Neuroinflammation-Assays-for-High-Throughput-In-Vitro-Screening.pdf | discovery | neuroinflammation | cell-line | |
| An AAV2-A53T Mouse Model Mimics Key Pathologies of Parkinson's Disease: α-Synuclein Aggregation, Dopaminergic Loss, and Neuroinflammation | 2025 | Discovery | Parkinson's disease | A53T-alpha-synuclein, Alpha-synuclein mouse models | Parkinson's disease, substantia nigra, caudate putamen, a-syn aggregation, dopaminergic loss | Rethmeier R., Krassnig S., Loeffler T., Daurer M., Breznik L., Neddens J., Flunkert S., Prokesch M. | Scantox Neuro GmbH, Grambach, Austria | scantox.com/scantox_poster-an-aav2-a53t-mouse-model-mimics-key-pathologies-of-parkinsons-disease-%ce%b1-synuclein-aggregation-dopaminergic-loss-and-neuroinflammation/ | discovery | parkinsons-disease | a53t-alpha-synuclein alpha-synuclein-mouse-models | |
| Human A53T-Mutated Synuclein Mouse Model with Disturbed Nigro-Striatal System to Study Parkinson’s Disease | 2025 | Discovery | Parkinson's disease | Alpha-synuclein mouse models | Dopamine transporter, Neuroinflammation, Activated microglia, T-cell infiltration, in situ hybridization, tyrosine hydroxylase | Breznik L., Daurer M., Loeffler T., Flunkert S., Prokesch M. | Scantox Neuro GmbH, Grambach, Austria | AD/PD 2025, Vienna | scantox.com/wp-content/uploads/2025/07/Scantox-Poster-Human-A53T-Mutated-Synuclein-Mouse-Model-with-Disturbed-Nigro-Striatal-System-Apr.2025.pdf | discovery | parkinsons-disease | alpha-synuclein-mouse-models |
| Evaluation of Cognitive Function in 4-and 6-months Old Line 61 Mice | 2025 | Discovery | Parkinson's disease | Line 61 mice | Cognition, Morris water maze, Wire hanging test, Y-maze test, Passive avoidance test, Search strategy, Irwin test | Rabl R., Fantina-Woblistin A., Daurer M., Breznik L., Loeffler T., Prokesch M. | Scantox Neuro GmbH, Grambach, Austria | AD/PD 2025, Vienna | scantox.com/wp-content/uploads/2025/07/Scantox-Poster-Evaluation-of-Cognitive-Function-in-4-and-6-Months-Old-Line-61-Mice-Apr.2025.pdf | discovery | parkinsons-disease | line-61-mice |
| Longitudinal Evaluation of pTHR217 Tau and Other Tau Sites in PS19 | 2025 | Discovery | Alzheimer's disease | PS19 | Brain, Cortex, Hippocampus, Plasma, CSF, NFL, GFAP, pThr217 tau, pSer202/2025 tau, | Perez Ruiz I., Loeffler T., Breznik L., DaurerM., Prokesch M. | Scantox Neuro GmbH, Grambach, Austria | AD/PD 2025, Vienna | scantox.com/wp-content/uploads/2025/07/Scantox-Poster-Longitudinal-Evaluation-of-pTHR217-Tau-and-Other-Tau-Sites-in-PS19-Apr.2025.pdf | discovery | alzheimers-disease | ps19 |
| Comparative Analysis of Human and Mouse Fibroblast Lines as In Vitro Models for Lysosomal Storage Diseases: A Focus on Enzyme Activity and Lipid Metabolism | 2025 | Discovery | Gaucher disease, Niemann-Pick disease, Pompe Disease | 4L/PS-NA mice, Cell line, NPC1 mice, Pompe 6neo | Lysosomal storage disease, Lipid accumulation, Glucocerebrosidase, α-glucosidase, Live-cell imaging | Loeffler T., Perez-Ruiz I., Loecker A., Schilcher I., Scheytt R., Daurer M., Flunkert S., Zdouc A., Breznik L., Brunner D., Prokesch M. | Scantox Neuro GmbH, Parkring 12, 8074 Grambach, Austria | WORLD Symposium 2025, San Diego | scantox.com/wp-content/uploads/2025/04/Scantox-Poster-Comparative-Analysis-of-Human-and-Mouse-Fibroblast-Lines-as-In-Vitro-Models-.-Feb.2025.pdf | discovery | gaucher-disease niemann-pick-disease pompe-disease | 4l-ps-na-mice cell-line npc1-mice pompe-6neo |
| Application of Preclinical Gene Therapy Approaches | 2025 | Discovery | Alzheimer's disease, Amyotrophic lateral sclerosis, Gaucher disease, Other, Parkinson's disease | 4L/PS-NA mice, Cell line, Mice, rat | Administration routes, Surgery, CSF sampling, Cell viability, Cell toxicity, Neurofilament light chain, | Krassnig S., Daurer M., Loeffler T., Flunkert S., Brunner D., Prokesch M. | Scantox Neuro GmbH, Parkring12, 8074 Grambach, Austria | WORLD Symposium 2025, San Diego | scantox.com/wp-content/uploads/2025/04/Scantox-Poster-Application-of-Preclinical-Gene-Therapy-Approaches-Feb.2025.pdf | discovery | alzheimers-disease amyotrophic-lateral-sclerosis gaucher-disease other parkinsons-disease | 4l-ps-na-mice cell-line mice rat |
| Longitudinal NF-L Measurements in In Vivo CSF Samples for Tracking Pathology Progression in Mouse Models of Gaucher and Niemann-Pick Disease | 2025 | Discovery | Gaucher disease, Niemann-Pick disease | 4L/PS-NA mice, NPC1 mice | Lysosomal storage disease, Neurodegeneration, Biomarker, Longitudinal sampling, Neurofilament light chain, NPC1-/-, 4L/PS-NA | Loeffler T., Brunner D., MernikB., Plattner K., NeddensJ., Breznik L., Daurer M., Flunkert S., Prokesch M. | Scantox Neuro GmbH, Parkring12, 8074 Grambach, Austria | WORLD Symposium 2025, San Diego | scantox.com/wp-content/uploads/2025/04/Scantox-Poster-Longitudinal-NF-L-Measurements-in-In-Vivo-CSF-Samples-for-Tracking-Pathology-.-Feb.2025.pdf | discovery | gaucher-disease niemann-pick-disease | 4l-ps-na-mice npc1-mice |
| Compound Muscle Action Potential as Translational Biomarker in a Mouse Model of Pompe Disease | 2025 | Discovery | Pompe Disease | Pompe 6neo | Lysosomal storage disease, Electromyography, Alpha-glucosidase, CMAP | Krassnig S., Breznik L., Ljekaj M., Fantina-Woblistin A., Daurer M., Flunkert S., Prokesch M. | Scantox Neuro GmbH, Parkring12, 8074 Grambach, Austria | WORLD Symposium 2025, San Diego | scantox.com/wp-content/uploads/2025/04/Scantox-Poster-Compound-Muscle-Action-Potential-as-Translational-Biomarker-in-a-Mouse-Model-of-Pompe-Disease-Feb.2025.pdf | discovery | pompe-disease | pompe-6neo |
| Comparative Analysis of In Vitro Systems for TDP-43 Pathology | 2024 | Discovery | Alzheimer's disease, Amyotrophic lateral sclerosis, Frontotemporal lobar degeneration, Parkinson's disease | iPSCs, Neuroblastoma cells | TDP-43, Stress granules, Cryptic splicing, Sodium arsenite | Stefanie Krassnig, Tina Loeffler, Irene Schilcher, Irantzu Perez Ruiz, Magdalena Daurer, Stefanie Flunkert, Manuela Prokesch | Scantox Neuro GmbH, Neuropharmacology, Grambach, Austria | scantox.com/wp-content/uploads/2024/09/Scantox_Neuro4D_2024-In-vitro-TDP43-Models.pdf | discovery | alzheimers-disease amyotrophic-lateral-sclerosis frontotemporal-lobar-degeneration parkinsons-disease | ipscs neuroblastoma-cells | |
| Longitudinal Analysis of a Nitroglycerin-Induced Mouse Migraine Model | 2024 | Discovery | Migraine | Mice | Grimace scale, Grooming, Light/dark box, Sex differences | Aaron Fantina-Woblistin, Livia Breznik, Laurenz Jauk, Magdalena Daurer, Roland Rabl, Tina Löffler, Manuela Prokesch | Scantox Neuro GmbH, Neuropharmacology, Grambach, Austria | Migraine Trust Int. Symposium 2024, London | scantox.com/wp-content/uploads/2024/09/Scantox-Neuro-MTIS_2024-Migraine-animal-model.pdf | discovery | migraine | mice |
| Behavioral and Histological Hallmarks of an Intrastriatal Rotenone Mouse Model for Parkinson's Disease | 2024 | Discovery | Parkinson's disease | C57BL6 mice | Rotenone, ER-stress, intrastriatal injection, motor deficits, neuroinflammation, neurodegeneratios | Paula Jauregi1,2, Roland Rabl1, Magdalena Daurer1, Livia Breznik1, Stefanie Flunkert1, Boris Chagnaud2, Manuela Prokesch1 | 1 Scantox Neuro GmbH, A-8074, Parkring 12, Grambach, Austria | FENS 2024, Vienna | scantox.com/wp-content/uploads/2024/11/FENS2024-poster-ER-stress-Rotenone.pdf | discovery | parkinsons-disease | c57bl6-mice |
| LPS and Pre-Aggregated Aβ1-42 Lead to an Increased Neuroinflammatory Response in Cerebral Organoids | 2024 | Discovery | Alzheimer's disease, Neuroinflammation | Cerebral Organoids | Neuroinflammation, LPS, Aβ1-42, cerebral organoids | Izaskun Itxaso1,2, Tina Loeffler1, Irene Schilcher1, Magdalena Daurer1, Stefanie Flunkert1, Boris Chagnaud2, Manuela Prokesch1 | 1 Scantox Neuro GmbH, A-8074, Parkring 12, Grambach, Austria | FENS 2024, Vienna | scantox.com/wp-content/uploads/2024/11/FENS2024_Poster_Cerebral-organoids.pdf | discovery | alzheimers-disease neuroinflammation | cerebral-organoids |
| Viral Gene Delivery Approach to Mimic α-Synuclein Pathology in a Preclinical Model for Parkinson`s Disease | 2024 | Discovery | Parkinson's disease | C57BL6 mice | Unilateral, substantia nigra, AAV-vector, caudate putamen | Stefanie Krassnig, Tina Loeffler, Magdalena Daurer, Livia Breznik, Joerg Neddens, | Scantox Neuro GmbH, Neuropharmacology, Grambach, Austria | ESGCT 2024, Rome | scantox.com/wp-content/uploads/2024/11/ESGCT2024_AAV-A53T-poster.pdf | discovery | parkinsons-disease | c57bl6-mice |
| Characterization of an Inducible AAV9-hTDP-43 Mouse Model for ALS | 2024 | Discovery | Amyotrophic lateral sclerosis | C57BL6 mice | Neurodegeneration, motor deficits, astrocytosis, atrophy, motor cortex | Benedikt Kien, Livia Breznik, Magdalena Daurer, Tina Loeffler, Laurenz Jauk, Stefanie Flunkert, Manuela Prokesch | Scantox Neuro GmbH, Neuropharmacology, Grambach, Austria | ESGCT 2024, Rome | scantox.com/wp-content/uploads/2024/11/ESGCT2024_AAV-TDP43-poster.pdf | discovery | amyotrophic-lateral-sclerosis | c57bl6-mice |
| Advancements in Preclinical Gene Therapy | 2024 | Discovery | n/a | 4L/PS-NA mice, Cell line, Rats | Compound administration routes, surgery techniques, in vivo CSF sampling, cell viability, toxicology, MTT assay, antisense oligonucleotides (ASO), | S Sharghi1, M Daurer1, T Loeffler1, S Flunkert1, D Brunner1, L Bruhn Madsen2, | 1 Scantox Neuro GmbH, A-8074, Parkring 12, Grambach, Austria | ESGCT 2024, Rome | scantox.com/wp-content/uploads/2024/11/ESGCT2024_Advancements-in-preclinical-gene-therapy-poster.pdf | discovery | n-a | 4l-ps-na-mice cell-line rats |
| AAV-Human A53T-Mutated Synuclein Disrupts Nigro-Striatal System in Mice | 2024 | Discovery | Parkinson's disease | C57BL6 mice | Parkinson's disease, pathology, histology, unilateral, substantia nigra, caudate putamen | Ewald Auer, Tina Loeffler, Magdalena Daurer, Livia Breznik, Joerg Neddens, Stefanie Flunkert, Manuela Prokesch | Scantox Neuro GmbH, Parkring 12, 8074 Grambach, Austria | scantox.com/wp-content/uploads/2024/11/SfN2024-AAV-A53T-poster.pdf | discovery | parkinsons-disease | c57bl6-mice | |
| Modeling Depression in Rats: Chronic Corticosterone Administration as a Tool for Antidepressant Efficacy Assessment | 2024 | Discovery | Depression | Rats | Behavior, Sucrose preference, Open field, Forces Swim test, Grooming, Coat Score | Ewald Auer, Aaron Fantina-Woblistin, Livia Breznik, Magdalena Daurer, Stefanie Flunkert, Manuela Prokesch | Scantox Neuro GmbH, Parkring 12, 8074 Grambach, Austria | SfN Neuroscience 2024, Chicago | scantox.com/wp-content/uploads/2024/11/SfN2024-Depression_poster.pdf | discovery | depression | rats |
| Accelerated Aging and Senescence in Cerebral Organoids | 2024 | Discovery | n/a | Cerebral Organoids | D-Galactose induction, senescence | Tina Loeffler, Izaskun Itxaso, Irene Schilcher, Irantzu Perez Ruiz, Magdalena Daurer, Stefanie Flunkert, Manuela Prokesch | Scantox Neuro GmbH, Parkring 12, Grambach, Austria | SfN Neuroscience 2024, Chicago | scantox.com/wp-content/uploads/2024/11/SfN2024-Organoids_poster.pdf | discovery | n-a | cerebral-organoids |
| In Vitro Systems Targeting TDP-43 Translocation, Stress Granules, and Stathmin-2 Splicing | 2024 | Discovery | Amyotrophic lateral sclerosis | Cell line, iPSCs | mRNA, alternative splicing, translocation, stress granule formation, cytosolic, nuclear | Andy Brown1, Tina Loeffler2, Irene Schilcher2, Irantzu Perez Ruiz2, Igor Cancar2, Magdalena Daurer2, Stefanie Flunkert2, | 1 Scantox Denmark ApS, Hestehavevej 36, 4623 Lille Skensved, Denmark | SfN Neuroscience 2024, Chicago | scantox.com/wp-content/uploads/2024/11/SfN2024-TDP-in-vitro_poster.pdf | discovery | amyotrophic-lateral-sclerosis | cell-line ipscs |
| Mating of Göttingen Minipigs at Scantox for use in embryofoetal development studies | 2022 | Regulatory Toxicology | n/a | Göttingen Minipig | Estrous synchronization | Ellemann-Laursen, Sisse | Scantox A/S, Denmark | Eurotox 2022, Maastricht | scantox.com/wp-content/uploads/2022/09/2022-09-SE-ETS-repro-Antwerp-1200x1400mm-v.3-final.pdf | regulatory-toxicology | n-a | gottingen-minipig |
