Multi-Channel Imaging to Visualize Renal Inflammation in an Alport Disease Mouse Model
While we are specialists for neuronal tissue, we also routinely process tissue of peripheral organs:
Kidney of the Alport syndrome mouse model Col4A3-/- was labeled for macrophages and leukocytes (Fig.1) as well as T-lymphocytes and macrophages (Fig.2), followed by automated slide scanning.
Figure 1: Immunofluorescent labeling for macrophages (F4/80) and leukocytes (CD45). A: whole kidney. B and C: detail of A in wild type (B) and Col4A3-/- mice (C).
Figure 2: Immunofluorescent labeling for T-lymphocytes (CD3) and macrophages (CD68). A: whole kidney. B and C: detail of A in wild type (B) and Col4A3-/- mice (C).
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