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Alzheimer’s Disease In Vitro Models
Aβ Induced Toxicity
Aβ Peptide Formation or Screening for Secretase Inhibitors
Determination of Aβ Aggregates
Tau Hyperphosporylation
Tau Uptake and Seeding
Tau Aggregation In Vitro
Parkinson’s Disease In Vitro Models
PD-Specific Lesion-Induced Neurotoxicity
Mitochondrial Impairment
α-synuclein Aggregation, Seeding and Autophagy
Neuronal Plasticity
Neurogenesis
Neurite Outgrowth
Synaptogenesis
Neuronal Activity
Neuroinflammation
BV-2 cells
Primary Mouse Microglia
Organotypic Hippocampal Brain Slices
Human iPSC-Derived Microglia
Phagocytosis
Lesion Induced In Vitro Models
Sodium Arsenite-Induced Stress Granule Formation
Excitotoxicity: L-Glutamate-Induced Lesion of Neuronal Cells
Neuronal Survival: Growth Factor Withdrawal
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Alzheimers Disease Transgenic Mouse Models
APP
SL
Transgenic Mouse Model
APP
SL
x hQC Transgenic Mouse Model
5xFAD Transgenic Mouse Model
Tg2576 Transgenic Mouse Model
TMHT Transgenic Mouse Model
hTau Transgenic Mouse Model
PS19 Transgenic Mouse Model
Parkinsons Disease Transgenic Mouse Models
D-Line Transgenic Mouse Model
Line 61 Transgenic Mouse Model
hA53Ttg Transgenic Mouse Model
LRRK2 G2019S KI/KI Mouse Model
LRRK2 G2019S Rat Model
MJFF Mouse Models
Amyotrophic Lateral Sclerosis Transgenic Mouse Models
SOD1-G93A Transgenic Mouse Model
SOD1-G93A/low Transgenic Mouse Model
TDP-43 Transgenic Mouse Models
Huntington’s Disease Models
R6/2 Transgenic Mouse Model
zQ175 Transgenic Mouse Model
BACHD Transgenic Rat Model
Lysosomal Storage Disease Models
NPC1
-/-
Mouse Model
4L/PS-NA Transgenic Mouse Model
GBA D409V KI Mouse Model
Pompe 6
neo
Mouse Model
Mucopolysaccharidosis IIIA Mouse Model
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Alzheimer’s Disease
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Gaucher Disease
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BTBR T+ tf/J Mouse Model
Fmr1
-KO Mouse Model
Nlrp3
A350VneoR
Mouse Model
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Irwin Test
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Open Field Test
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Morris Water Maze Test
Novel Object Recognition Test
Passive Avoidance Test
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Y-Maze Test
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Grip Strength
Pasta Gnawing Test
Pole Test
RotaRod Test
Wire Hanging Test
Electrophysiology (CMAP, MUNE)
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Elevated Plus Maze
Forced Swim Test
Marble Burying Test
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Three Chamber Social Test
Lateral Lesion Tests
Corner Turn Test
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Cylinder Test
Rotation Test
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Col4A3 Knockout Mouse Model
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Ames II and Ames MPF Test
Ames 24-well Agar Test
Full Plate Ames Test
Clastogens and Aneugens
MicroFlow Flow MNT Test
Multiflow® Test
96-Well MNT and FISH Test
OECD 487 In Vitro Micronucleus Test
All Mechanisms
BlueScreen HC
Multiflow® Test
GLP Genotoxicity Services
GLP OECD 471 Ames Test
OECD 487 In Vitro Micronucleus Test
OECD 490 GLP Mouse Lymphoma Assay (MLA)
OECD 476: HPRT Assay
OECD 474: In Vivo Micronucleus Test
OECD 488: Big Blue® Transgenic Rodent Somatic and Germ Cell Gene Mutation Assay Test
GLP Skin and Ocular Toxicology
GLP Skin Toxicology
OECD 431: In Vitro Skin Corrosion Test using Reconstructed Human Epidermis (RhE)
OECD 439: In Vitro Skin Irritation Test using Reconstructed Human Epidermis (RhE)
OECD 432: Phototoxicity Test
GLP Ocular Toxicology Studies
OECD 437: Bovine Corneal Opacity and Permeability Test (BCOP)
OECD 492: EpiOcular™ Eye Irritation Test
Skin Sensitisation Tests
OECD 442C: Direct Peptide Reactivity Assay Test
OECD 442D KeratinoSens™ Test
OECD 442E: h-CLAT Test
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Juvenile Toxicology Studies in Minipigs
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Humanized lgG Göttingen Minipigs
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Plasma pharmacokinetic and metabolism of [18F]THK-5317 are dependent on sex
Plasma pharmacokinetic and metabolism of [18F]THK-5317 are dependent on sex
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