logo-white
連絡先
Search
Close this search box.

MJFFマウスモデル

研究者の時間とリソースを節約するために、マイケル・J・フォックス財団は、科学コミュニティに多くのツールを短納期かつ低コストで提供しています。 SCANTOXは以下のMJFFマウスモデルをお客様に提供する権利を得ており、これらのモデルを用いた研究を喜んでお引き受けいたします。

Ninja Column 1Ninja Column 2Ninja Column 3Ninja Column 4Ninja Column 5Ninja Column 6
Target
Common Name
Allele Type
JAX strain
Description
Active link
LRRK1LRRK1 KOKnockout16120knockout exons 24 throught 29 of Lrrk1https://www.jax.org/strain/016120
LRRK1LRRK1 KOKnockout22880knockout exons 24 throught 29 of Lrrk1, no Pde6bhttps://www.jax.org/strain/022880
LRRK1 and LRRK2LRRK1/2 double KO16122knockout exons 24 throught 29 of Lrrk1 and knockout exons 39 throught 40 of Lrrk2https://www.jax.org/strain/016122
LRRK2BAC Human LRRK2 wildtypeKnockout13725BAC transgene expresisng WT LRRK2 enodgenouse promotorhttps://www.jax.org/strain/013725
LRRK2BAC Human LRRK2 R1441GTransgenic18786BAC LRRK2(R1441G) enodenous promotorhttps://www.jax.org/strain/018786
LRRK2BAC Human LRRK2 G2019STransgenic18785BAC LRRK2 (G2019S) transgenehttps://www.jax.org/strain/018785
LRRK2LRRK2 KOTransgenic16121knockout exons 39 throught 40 of Lrrk2https://www.jax.org/strain/016121
LRRK2LRRK2 D1994A KIKnockout21830D1994A point mutation in Lrrk2https://www.jax.org/strain/021830
LRRK2LRRK2 T1348N KIKnockin21829T1348N point mutation in Lrrk2https://www.jax.org/strain/021829
LRRK2LRRK2 A2016T KIKnockin21828A2016T point mutation in Lrrk2https://www.jax.org/strain/021828
SNCABAC Human alphasynuclein wildtypeKnockin18442BAC murine promotor Human WT SNCAhttps://www.jax.org/strain/018442
SNCAmThy-1 Human alpha-synucleinTransgenic16936Murine Thy1 promotor, human WT SNCAhttps://www.jax.org/strain/016936
SNCAmThy-1 Human alpha-synucleinTransgenic17682Murine Thy1 promotor, human WT SNCAhttps://www.jax.org/strain/017682
SNCAAlpha-synuclein KOKnockout16123knockout exons 1 through 4 of murine SNCAhttps://www.jax.org/strain/016123
Eif4g1Eif4g1 R1207HKnockin24521R1207H in exon 24, as well as loxP sites flanking exons 24 to 28. Crebmediated recombination removes exon 24 to 28 resulting in null allele.https://www.jax.org/strain/024521
Eif4g1Eif4g1 KOConditional Knockout21827LoxP sites flanking exons 24 to 28. Creb-mediated recombination removed exon 24 to 28 resulting in null allele.https://www.jax.org/strain/021827
VPS35VPS35 D620N KIKnockin23409D620N mutation in exon 15https://www.jax.org/strain/023409
VPS35VPS35 D620N KIfloxΔneo Vps35Conditional Knockout21807Cre recombinase inducible D620N mutation in exon 15https://www.jax.org/strain/021807
GBAGBA D409V KIKnockin19106Gba D427V mutant protein corresponse to D409Vhttps://www.jax.org/strain/019106

お問い合わせをお待ちしております。

科学ニュース

ニュースレター

最新ニュースに簡単にアクセスできる！

サブスクライブ