| Title | Category | Keywords | Read more | Scantox Business Unit | Disease | Document ID | Document updated | More information | hf:tax:flyers_pdf_category | hf:tax:division | hf:tax:disease |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 24-well 'Mini Ames' Agar Based Screen | Genotox | Screening, TA98 & TA100, mutagenicity, point mutations, bacterial reverse mutation assay, plate incorporation | scantox.com/wp-content/uploads/2024/11/155-71-24wellMiniAmes-EN.pdf | Genetic Toxicology | n/a | 155-71-24wellMiniAmes-EN | 10/2024 | scantox.com/services/genotox/genetic-toxicology-testing/mutagens/ames-24-well-agar/ | genotox | genetic-toxicology | n-a |
| 5xFAD Transgenic Mouse Model | Animal Models | Abeta, Amyloid-beta, Plaque, Hippocampus, Neuroinflammation, Neurodegeneration, Astrocytosis, Vascular pathology, Memory deficits | scantox.com/wp-content/uploads/2024/10/126-55-AD5xFAD-EN.pdf | Discovery | Alzheimer's disease | 126-55-AD5xFAD-EN | 04/2024 | scantox.com/services/discovery/animal-models/alzheimers-disease-transgenic-mouse-models/5xfad-transgenic-mouse-model/ | animal-models | discovery | alzheimers-disease |
| 6-OHDA-Induced Mouse Model | Animal Models | Motor deficits, Tyrosine hydroxylase, L-DOPA, DOPAC, HVA | scantox.com/wp-content/uploads/2024/03/126-26-Parkinsons6OHDA-EN.pdf | Discovery | Parkinson's disease | 126-26-Parkinsons6OHDA-EN | 04/2024 | scantox.com/services/discovery/animal-models/induced-disease-models/parkinsons-disease/#6ohda | animal-models | discovery | parkinsons-disease |
| Abeta and Tau Aggregation | In Vitro Models | Thioflavin T, A4 assay, Amyloid-beta, Disaggregation | scantox.com/wp-content/uploads/2024/03/126-56-AbetaTau-EN.pdf | Discovery | Alzheimer's disease | 126-56-AbetaTau-EN | 04/2024 | scantox.com/services/discovery/in-vitro-services/alzheimers-disease-in-vitro-models/ | in-vitro-models | discovery | alzheimers-disease |
| CAPS mouse | Animal Models | Cryopyrin-associated periodic syndrome, Muckle-Wells syndrome, Familial cold autoinflammatory syndrome, FCAS, Neonatal-onset multisystem inflammatory disease, NOMID, Body weight, Dermatitis | scantox.com/wp-content/uploads/2024/03/126-49-AIDCAPS-EN.pdf | Discovery | Autoinflammatory Diseases | 126-49-AIDCAPS-EN | 04/2024 | animal-models | discovery | autoinflammatory-diseases | |
| Col4A3 Knockout Mouse Model | Animal Models | Body weight, Kidney, Renal function, Survival, Ramipril, Motor deficits | scantox.com/wp-content/uploads/2024/03/126-48-AlportCol4a3-EN.pdf | Discovery | Alport Syndrome | 126-48-AlportCol4a3-EN | 04/2024 | scantox.com/services/discovery/other/kidney-diseases/col4a3-knockout-mouse-model/# | animal-models | discovery | alport-syndrome |
| Ames MPF/II Liquid based Fluctuation Test | Genotox | Screening, reduced liquid microplate format, TA98, TA100, TA1535, TA1537, mutagenicity, point mutations, colorimetric, fluctuation tests, bacterial reverse mutation | scantox.com/wp-content/uploads/2024/11/155-72-AmesMPFII-EN.pdf | Genetic Toxicology | n/a | 155-72-AmesMPFII-EN | 10/2024 | scantox.com/services/genotox/genetic-toxicology-testing/mutagens/ames-2-mpf/ | genotox | genetic-toxicology | n-a |
| Ames Test | Genotox | GLP, plate incorporation, pre-incubation, TA98, TA100, TA1535, TA1537, TA102, TA97, TA97a, uvrA/pKM101, WP2 pKM101, WP2 uvrA, mutagenicity, point mutations, bacterial reverse mutation, OECD471 | scantox.com/wp-content/uploads/2024/11/155-83-OECD471-EN.pdf | Genetic Toxicology | n/a | 155-83-OECD471-EN | 01/2025 | scantox.com/services/genotox/regulatory-genotoxicity-studies/oecd-471-ames-test/ | genotox | genetic-toxicology | n-a |
| Ames Test with Enhanced Conditions | Genotox | Bacterial reverse mutation, N-nitrosamines, N-nitrosamine drug substance related impurities (NDSRIs), pre-incubation, N-nitroso-dimethylamine (NDMA), 1-Cyclopentyl-4-nitrosopiperazine, GLP, OECD471 | scantox.com/wp-content/uploads/2024/11/155-76-OECD471Ames-EN.pdf | Genetic Toxicology | n/a | 155-76-OECD471Ames-EN | 01/2025 | scantox.com/services/genotox/regulatory-genotoxicity-studies/oecd-471-ames-test/ | genotox | genetic-toxicology | n-a |
| In vivo Services | Services | Animal maintenance, Housing, Treatment, In vivo tissue collection, Behavioral tests, Tissue Sampling | scantox.com/wp-content/uploads/2024/03/126-16-AnimalFacility-EN.pdf | Discovery | n/a | 126-16-AnimalFacility-EN | 04/2024 | scantox.com/services/discovery/in-vivo-services/ | services | discovery | n-a |
| APPSL Transgenic Mouse Model | Animal Models | Learning, Memory deficits, Morris water maze, Abeta, Amyloid-beta, Plaques, Microgliosis, Astrocytosis, Neuroinflammation, Oxidative stress | scantox.com/wp-content/uploads/2024/03/126-54-ADAPPSL-EN.pdf | Discovery | Alzheimer's disease | 126-54-ADAPPSL-EN | 04/2024 | scantox.com/services/discovery/animal-models/alzheimers-disease-transgenic-mouse-models/appsl-transgenic-mouse-model/ | animal-models | discovery | alzheimers-disease |
| BTBR T+ tf/J Mouse Model | Animal Models | Social behavior, Repetitive behavior, Anxiety, Learning, Muscle strength | scantox.com/wp-content/uploads/2024/03/126-43-ASDBTBR-EN.pdf | Discovery | Autism spectrum disorder | 126-43-ASDBTBR-EN | 04/2024 | scantox.com/services/discovery/animal-models/btbr-t-tf-j-mouse-model/ | animal-models | discovery | autism-spectrum-disorder |
| Aβ Seeding - Alzheimer's Disease | In Vitro Models | Aggregation, Abeta, Oligomers, Oligomerization, A4 assay | scantox.com/wp-content/uploads/2025/01/126-60-AbetaSeeding-EN.pdf | Discovery | Alzheimer's disease | 126-60-AbetaSeeding-EN | 01/2025 | scantox.com/services/discovery/in-vitro-services/alzheimers-disease-in-vitro-models/ | in-vitro-models | discovery | alzheimers-disease |
| BACHD Transgenic Rat Model | Animal Models | Huntingtin, Aggregation | scantox.com/wp-content/uploads/2024/03/126-36-HuntingtonsBACHD-EN.pdf | Discovery | Huntington's disease | 126-36-HuntingtonsBACHD-EN | 04/2024 | scantox.com/services/discovery/animal-models/huntingtons-disease-mouse-models/bachd-transgenic-rat-model/ | animal-models | discovery | huntingtons-disease |
| Bioanalysis | Services | Sample processing, Sample analysis, Protein, RNA, DNA, Biomarker | scantox.com/wp-content/uploads/2024/12/126-15-Bioanalysis-EN.pdf | Discovery | n/a | 126-15-Bioanalysis-EN | 11/2024 | scantox.com/services/discovery/ex-vivo-services/molecular-biology-biomarker-analytics/ | services | discovery | n-a |
| Biobank | Services | Mouse models, Tissue, Brain, Spinal cord, Hippocampus, Cortex, Striatum, Muscle, Liver, Kidney | scantox.com/wp-content/uploads/2024/12/126-69-Biobank-EN.pdf | Discovery | Alzheimer's disease, Amyotrophic lateral sclerosis, Frontotemporal lobar degeneration, Gaucher disease, Huntington's disease, Lewy body dementia, Multiple Sclerosis, Neuroinflammation, Niemann-Pick disease, Parkinson's disease, Tauopathies | 126-68-Biobank-EN | 11/2024 | scantox.com/services/discovery/ex-vivo-services/biobank/ | services | discovery | alzheimers-disease amyotrophic-lateral-sclerosis frontotemporal-lobar-degeneration gaucher-disease huntingtons-disease lewy-body-dementia multiple-sclerosis neuroinflammation niemann-pick-disease parkinsons-disease tauopathies |
| Haloperidol-Induced Catalepsy | Animal Models | Epilepsy, Catatonia, Schizophrenia, Seizures, Consciousness, Rigidity, Haloperidol | scantox.com/wp-content/uploads/2024/03/126-41-CatalepsyHaloperidole-EN.pdf | Discovery | Parkinson's disease | 126-41-CatalepsyHaloperidole-EN | 04/2024 | scantox.com/services/discovery/animal-models/induced-disease-models/parkinsons-disease/ | animal-models | discovery | parkinsons-disease |
| Cell Culture Models | Services | Cells type, Genetic modification, Lesion, Treatment, Sample processing, Measurement | scantox.com/wp-content/uploads/2024/03/126-14-CellCulture-EN.pdf | Discovery | n/a | 126-14-CellCulture-EN | 04/2024 | scantox.com/services/discovery/in-vitro-services/cell-culture-models/ | services | discovery | n-a |
| D-Line Transgenic Mouse Model | Animal Models | Alpha-synuclein, Accumulation, Lewy bodies, Striatum, Dopamine, Atrophy | scantox.com/wp-content/uploads/2024/03/126-24-ParkinsonsDLine-EN.pdf | Discovery | Parkinson's disease | 126-24-ParkinsonsDLine-EN | 04/2024 | scantox.com/services/discovery/animal-models/parkinsons-disease-transgenic-mouse-models/d-line-transgenic-mouse-model/ | animal-models | discovery | parkinsons-disease |
| Special Diet Induced Models | Animal Models | Body weight, Food consumption, Whole gut transit time, Glucose tolerance, Activity, Learning, Memory, Evans Blue, Blood-brain barrier | scantox.com/wp-content/uploads/2024/03/126-40-DietInducedModels-EN.pdf | Discovery | Other | 126-40-DietInducedModels-EN | 04/2024 | scantox.com/services/discovery/animal-models/induced-disease-models/special-diet/ | animal-models | discovery | other |
| Flow Micronucleus Test (Flow MNT) | Genotox | microflow, screening, flow cytometry, clastogens, aneugens | scantox.com/wp-content/uploads/2024/11/155-73-FlowMNT-EN.pdf | Genetic Toxicology | n/a | 155-73-FlowMNT-EN | 10/2024 | scantox.com/services/genotox/genetic-toxicology-testing/clastogens-aneugens/microflow-flow-mnt/ | genotox | genetic-toxicology | n-a |
| Fmr1-KO Mouse Model | Animal Models | Hyperactivity, Anxiety, Repetitive Behavior, Social Behavior, Vocalization | scantox.com/wp-content/uploads/2024/03/126-42-ASDFmr1KO-EN.pdf | Discovery | Autism spectrum disorder, Other | 126-42-ASDFmr1KO-EN | 04/2024 | scantox.com/services/discovery/animal-models/fmr1-ko-mouse-model/ | animal-models | discovery | autism-spectrum-disorder other |
| 4L/PS-NA Transgenic Mouse Model | Animal Models | Muscle weakness, Motor deficits, Glucoslceramide, Glucosylsphingosin, Neuroinflammation, Astrocytosis | scantox.com/wp-content/uploads/2024/12/126-39-Gaucher4LPSNA-EN.pdf | Discovery | Gaucher disease | 126-39-Gaucher4LPSNA-EN | 12/2024 | scantox.com/services/discovery/animal-models/lysosomal-storage-diseases/4l-ps-na-transgenic-mouse-model/ | animal-models | discovery | gaucher-disease |
| Conduritol-β-Epoxide (CBE)-Induced Mouse Model | Animal Models | Conduritol-B-Epoxide, Neuroinflammation, Astrocytosis, Microgliosis | scantox.com/wp-content/uploads/2024/12/126-38-GaucherCBE-EN.pdf | Discovery | Gaucher disease | 126-38-GaucherCBE-EN | 12/2024 | scantox.com/services/discovery/animal-models/induced-disease-models/gaucher-disease/ | animal-models | discovery | gaucher-disease |
| GBA D409V KI Mouse Model | Animal Models | GCase activity, Brain, Liver, Glucosylsphingosine, Alpha-synuclein | scantox.com/wp-content/uploads/2024/12/126-37-GaucherGBA-EN.pdf | Discovery | Gaucher disease | 126-37-GaucherGBA-EN | 12/2024 | scantox.com/services/discovery/animal-models/lysosomal-storage-diseases/gba-d409v-ki-mouse-model/ | animal-models | discovery | gaucher-disease |
| Gene Therapy Services | Services | AST/ALT/ALP, GGT, GLDH | scantox.com/wp-content/uploads/2024/09/Scantox_Brochure_Discovery_126-61-GeneTherapy_EN_WEB_opslag_18.09.24.pdf | Discovery | Alzheimer's disease, Amyotrophic lateral sclerosis, Cancer, Fabry disease, Frontotemporal lobar degeneration, Gaucher disease, Huntington's disease, Lewy body dementia, Niemann-Pick disease, Parkinson's disease, Tauopathies | 126-61-GeneTherapy-EN | 09/2024 | scantox.com/services/discovery/gene-therapy/ | services | discovery | alzheimers-disease amyotrophic-lateral-sclerosis cancer fabry-disease frontotemporal-lobar-degeneration gaucher-disease huntingtons-disease lewy-body-dementia niemann-pick-disease parkinsons-disease tauopathies |
| AAV2 hA53T-α-syn Induced Mouse Model | Animal Models | Substantia nigra, Caudate putamen, Ipsilateral, Microgliosis, Tyrosine hydroxylase | scantox.com/wp-content/uploads/2024/03/126-25-ParkinsonsA53Tvirus-EN.pdf | Discovery | Parkinson's disease | 126-25-ParkinsonsA53Tvirus-EN | 04/2024 | scantox.com/services/discovery/animal-models/induced-disease-models/parkinsons-disease/ | animal-models | discovery | parkinsons-disease |
| hA53Ttg Transgenic Mouse Model | Animal Models | Motor deficits, Muscle weakness, Neuroinflammation | scantox.com/wp-content/uploads/2024/03/126-23-ParkinsonsHA53Ttg-EN.pdf | Discovery | Parkinson's disease | 126-23-ParkinsonsHA53Ttg-EN | 04/2024 | scantox.com/services/discovery/animal-models/parkinsons-disease-transgenic-mouse-models/ha53ttg-transgenic-mouse-model/ | animal-models | discovery | parkinsons-disease |
| Histology Services | Services | Tissue processing, Immunohistology, Staining, Microscopy, Imaging, Immunofluorescence, Quantitative image analysis | scantox.com/wp-content/uploads/2024/03/126-13-Histology-EN.pdf | Discovery | n/a | 126-13-Histology-EN | 04/2024 | scantox.com/services/discovery/ex-vivo-services/histology-services/ | services | discovery | n-a |
| hTau Transgenic Mouse Model | Animal Models | Phosphorylation | scantox.com/wp-content/uploads/2024/03/126-53-ADhTau-EN.pdf | Discovery | Alzheimer's disease | 126-53-ADhTau-EN | 04/2024 | scantox.com/services/discovery/animal-models/alzheimers-disease-transgenic-mouse-models/htau-transgenic-mouse-model/ | animal-models | discovery | alzheimers-disease |
| In vitro Micronucleus Test | Genotox | GLP, fluorescent in situ hybridisation (FISH), pan-centromeric staining, clastogens, aneugens, TK6 cells, isolated human lymphocytes (HuLy), chromosomal damage, OECD487 | scantox.com/wp-content/uploads/2024/11/155-78-OECD487-EN.pdf | Genetic Toxicology | n/a | 155-78-OECD487-EN | 01/2025 | scantox.com/services/genotox/genetic-toxicology-testing/clastogens-aneugens/oecd-487-in-vitro-mnt/ | genotox | genetic-toxicology | n-a |
| In Vitro Neuroinflammation | In Vitro Models | LPS, BV2 cells, Microglia, Organotypic brain slices, Cytokines | scantox.com/wp-content/uploads/2024/03/126-33-InVitroNeuroinflammation-EN.pdf | Discovery | Neuroinflammation | 126-33-InVitroNeuroinflammation-EN | 04/2024 | scantox.com/services/discovery/in-vitro-services/neuroinflammation/ | in-vitro-models | discovery | neuroinflammation |
| In Vivo Induced Models by Indication | Services | Indication, Species, Induced, Reference compound, Readouts, Treatment route | scantox.com/wp-content/uploads/2024/12/126-84-InVivoInducedModels-EN.pdf | Discovery | n/a | 126-84-InVivoInducedModels | 12/2024 | scantox.com/services/discovery/animal-models/induced-disease-models/ | services | discovery | n-a |
| In vivo Micronucleus Assay | Genotox | Wistar Han rat, rodent micronucleus, bone marrow (slide scored), chromosomal damage, OECD474 | scantox.com/wp-content/uploads/2024/11/155-77-OECD474-EN.pdf | Genetic Toxicology | n/a | 155-77-OECD474-EN | 01/2025 | scantox.com/services/genotox/regulatory-genotoxicity-studies/oecd-474-in-vivo-micronucleus-test/ | genotox | genetic-toxicology | n-a |
| In Vivo Transgenic Models by Indication | Services | Indication, Species, Mutation, Construct, Promoter | scantox.com/wp-content/uploads/2024/03/126-10-InVivoTGModels-EN.pdf | Discovery | n/a | 126-10-InVivoTGModels-EN | 11/2024 | scantox.com/services/discovery/animal-models/ | services | discovery | n-a |
| Line 61 Transgenic Mouse Model | Animal Models | Motor deficits, Alpha-synuclein | scantox.com/wp-content/uploads/2024/03/126-22-ParkinsonsLine61-EN-1.pdf | Discovery | Parkinson's disease | 126-22-ParkinsonsLine61-EN | 10/2024 | scantox.com/services/discovery/animal-models/parkinsons-disease-transgenic-mouse-models/line-61-transgenic-mouse-model/ | animal-models | discovery | parkinsons-disease |
| CCl4-Induced Liver Fibrosis | Animal Models | Col1a1, Acta2, Hydroxyproline, Smooth muscle cell actin, SMA | scantox.com/wp-content/uploads/2024/03/126-32-LiverfibrosisCCL4-EN.pdf | Discovery | Liver Fibrosis | 126-32-LivrefibrosisCCL4-EN | 04/2024 | scantox.com/services/discovery/other/liver-diseases/liver-fibrosis/ | animal-models | discovery | liver-fibrosis |
| Lipopolysaccharide (LPS) Induced Neuroinflammation | In Vitro Models | LPS, CD68, Iba1, Microgliosis, Macrophages | scantox.com/wp-content/uploads/2024/03/126-31-LPSNeuroinflammation-EN.pdf | Discovery | Neuroinflammation | 126-31-LPSNeuroinflammatin-EN | 04/2024 | scantox.com/services/discovery/animal-models/induced-disease-models/neuroinflammation/ | in-vitro-models | discovery | neuroinflammation |
| LRRK2 Mouse | Animal Models | LRRK2, Phosphorylation, MLi-2 | scantox.com/wp-content/uploads/2024/10/126-57-ParkinsonsLRRK2Mouse-EN.pdf | Discovery | Parkinson's disease | 126-57-ParkinsonsLRRK2Mouse-EN | 04/2024 | animal-models | discovery | parkinsons-disease | |
| LRRK2 Rat | Animal Models | LRRK2, Phosphorylation, MLi-2 | scantox.com/wp-content/uploads/2024/10/126-58-ParkinsonsLRRK2Rat-EN.pdf | Discovery | Parkinson's disease | 126-58-ParkinsonsLRRK2Rat-EN | 04/2024 | animal-models | discovery | parkinsons-disease | |
| Micronucleus Assay 96-Well + FISH | Genotox | Screening, fluorescent in situ hybridisation (FISH), pan-centromeric staining, metafer automated scoring, clastogens, aneugens, TK6 cells | scantox.com/wp-content/uploads/2024/11/155-74-MicronucleusFISH-EN.pdf | Genetic Toxicology | n/a | 155-74-MicronucleusFISH-EN | 10/2024 | scantox.com/newsletters/fluorescent-in-situ-hybridization-fish-to-analyze-gene-expression/ | genotox | genetic-toxicology | n-a |
| Migraine | Animal Models | Grimace scale, Nociception, Nitroglycerine | scantox.com/wp-content/uploads/2024/10/126-59-MigraineNTGinduced-EN.pdf | Discovery | Migraine | 126-59-MigraineNTGinduced-EN | 04/2024 | animal-models | discovery | migraine | |
| Mouse Lymphoma Assay (MLA) | Genotox | GLP, mammalian gene mutation assay, L5178Y, thymidine kinase (Tk) locus, mouse thymic lymphoma, OECD490 | scantox.com/wp-content/uploads/2024/11/155-79-OECD490-EN.pdf | Genetic Toxicology | n/a | 155-79-OECD490-EN | 01/2025 | scantox.com/services/genotox/regulatory-genotoxicity-studies/oecd-490-mouse-lymphoma-assay-mla/ | genotox | genetic-toxicology | n-a |
| MPTP induced mouse | Animal Models | Hyperactivity, Activity, Motor deficits, DOPAC, HVA, Substantia nigra, Dopamine, | scantox.com/wp-content/uploads/2024/03/126-21-ParkinsonsMPTP-EN.pdf | Discovery | Parkinson's disease | 126-21-ParkinsonsMPTP-EN | 04/2024 | animal-models | discovery | parkinsons-disease | |
| MS-Cuprizone | Animal Models | MAO activity, Myelination, Neuroinflammation | scantox.com/wp-content/uploads/2024/09/126-30-MultipleSclerosisCuprizone-EN.pdf | Discovery | Multiple Sclerosis | 126-30-MultipleSclerosisCuprizone-EN | 04/2024 | animal-models | discovery | multiple-sclerosis | |
| MS-EAE induced | Animal Models | Clinical signs, Activity, Muscle strength, Motor deficits, Myelination, Neuroinflammation, Neurodegeneration | scantox.com/wp-content/uploads/2024/03/126-29-MultipleSclerosisEAE-EN.pdf | Discovery | Multiple Sclerosis | 126-29-MultipleSchlerosisEAE-EN | 04/2024 | animal-models | discovery | multiple-sclerosis | |
| Multiflow® | Genotox | Screening, point mutations, aneugens, clastogens, flow cytometry, biomarkers: p53, H2AX, H3, Polyploidy | scantox.com/wp-content/uploads/2024/11/155-75-MultiFlow-EN.pdf | Genetic Toxicology | n/a | 155-75-MultiFlow-EN | 10/2024 | scantox.com/services/genotox/genetic-toxicology-testing/clastogens-aneugens/multiflow/ | genotox | genetic-toxicology | n-a |
| Niemann-Pick-NPC1 ko mouse | Animal Models | Cholesterol, Lipid accumulation, Neuronal loss, Neuroinflammation, APP, amyloid-beta, Phosphorylation, Tau, Motor deficits | scantox.com/wp-content/uploads/2024/12/126-28-NiemannPick-EN.pdf | Discovery | Niemann-Pick disease | 126-28-NiemannPick-EN | 11/2024 | scantox.com/services/discovery/animal-models/lysosomal-storage-diseases/npc1-mouse-model/ | animal-models | discovery | niemann-pick-disease |
| Organotypic Brain Slices | In Vitro Models | LPS, 6-OHDA, Cytokine, Cell viability, Toxicity, Mitochondrial activity, mRNA expression, Protein levels, TNF-alpha, IL-1beta | scantox.com/wp-content/uploads/2024/03/126-27-OrganotypicBrainSlices-EN.pdf | Discovery | n/a | 126-27-OrganotypicBrainSlices-EN | 04/2024 | in-vitro-models | discovery | n-a | |
| Pompe 6neo mouse | Animal Models | GAA, brain, spinal cord, liver, muscle, Glycogen, Myofibrils, Muscle, Mobility, Body weight, Astrocytosis | scantox.com/wp-content/uploads/2024/12/126-20-Pompe-EN.pdf | Discovery | Pompe Disease | 126-20-Pompe-EN | 11/2024 | scantox.com/services/discovery/animal-models/lysosomal-storage-diseases/pompe-6neo-mouse/ | animal-models | discovery | pompe-disease |
| PS19 mouse | Animal Models | Phosphorylation, Atrophy, Neuronal loss, Neuroinflammation, Muscle weakness, Anxiety, Learning, Memory, Survival | scantox.com/wp-content/uploads/2024/12/126-52-ADPS19-EN.pdf | Discovery | Alzheimer's disease | 126-52-ADPS19-EN | 12/2024 | scantox.com/services/discovery/animal-models/alzheimers-disease-transgenic-mouse-models/ps19-transgenic-mouse-model/ | animal-models | discovery | alzheimers-disease |
| R6/2 mouse | Animal Models | Aggregates, Motor deficits, Learning, Survival | scantox.com/wp-content/uploads/2024/03/126-35-HuntingtonsR6_2-EN.pdf | Discovery | Huntington's disease | 126-35-HuntingtonsR6_2-EN | 04/2024 | animal-models | discovery | huntingtons-disease | |
| Rodent models of type II diabetes | Animal Models | Insulin resistance, Glucose intolerance, Hyperglycemia, Genetic model, Diet-induced model | scantox.com/wp-content/uploads/2024/04/122-64-Diabetes-EN.pdf | Discovery | Type-2 diabetes | 122-64-Diabetes-EN | 04/2024 | animal-models | discovery | type-2-diabetes | |
| Sanfilippo-MPSIIIA mouse | Animal Models | Learning, Memory, Social behavior, Neuroinflammation, Lysosomes | scantox.com/wp-content/uploads/2024/12/126-19-SanfilippoMSPIIIA-EN.pdf | Discovery | Sanfilippo Syndrome | 126-19-SanfilippoMSPIIIA-EN | 11/2024 | scantox.com/services/discovery/animal-models/lysosomal-storage-diseases/mucopolysaccharidosis-iiia/ | animal-models | discovery | sanfilippo-syndrome |
| SARS-CoV-2 Infection | Animal Models | Mice, Hamster, Ferret, hACE2, Survival, Body weight, Body temperature | scantox.com/wp-content/uploads/2024/07/123-67-SarsCov2-EN.pdf | Discovery | SARS-CoV | 123-67-SarsCov2-EN | 11/2024 | animal-models | discovery | sars-cov | |
| Schizophrenia-MK801 | Animal Models | Activity, Learning | scantox.com/wp-content/uploads/2024/03/126-18-SchizophreniaMK801-EN.pdf | Discovery | Schizophrenia | 126-18-SchizophreniaMK801-EN | 04/2024 | animal-models | discovery | schizophrenia | |
| Schizophrenia-PCP AMPH induced rat | Animal Models | Social behavior, Startle response, Prepulse inhibition | scantox.com/wp-content/uploads/2024/03/126-17-SchizophreniaInducibleRat-EN.pdf | Discovery | Other, Schizophrenia | 126-17-SchizophreniaInducibleRat-EN | 04/2024 | animal-models | discovery | other schizophrenia | |
| Scopolamine | Animal Models | Memory, Passive Avoidance | scantox.com/wp-content/uploads/2024/03/126-51-ADScopolamine-EN.pdf | Discovery | Alzheimer's disease | 126-51-ADScopolamine-EN | 04/2024 | animal-models | discovery | alzheimers-disease | |
| Screening Package #1 | Genotox | genotoxicity screening, ames, micronucleus test, 24-well, 96-well, clastogens, aneugens, point mutations | scantox.com/wp-content/uploads/2024/11/155-80-ScreeningPackage1-EN.pdf | Genetic Toxicology | n/a | 155-80-ScreeningPackage1-EN | 10/2024 | genotox | genetic-toxicology | n-a | |
| SOD1-G93A Transgenic Mouse Model | Animal Models | Accumulation, Spinal cord, Brain stem, Motor neuron loss, Neuronal loss, Neuroinflammation, Astrocytosis, Microgliosis, Motor deficits | scantox.com/wp-content/uploads/2025/01/126-47-ALSSOD1-EN.pdf | Discovery | Amyotrophic lateral sclerosis | 126-47-ALSSOD1-EN | 01/2025 | scantox.com/services/discovery/animal-models/amyotrophic-lateral-sclerosis-transgenic-mouse-models/sod1-g93a-transgenic-mouse-models/ | animal-models | discovery | amyotrophic-lateral-sclerosis |
| SOD1-low expressor mouse | Animal Models | Survival, Body weight, Clasping, Muscle deficits, Clinical signs | scantox.com/wp-content/uploads/2024/03/126-46-ALSSOD1LowExpressor-EN.pdf | Discovery | Amyotrophic lateral sclerosis | 126-46-ALSSOD1LowExpressor-EN | 04/2024 | animal-models | discovery | amyotrophic-lateral-sclerosis | |
| Spine Density Analysis | Services | Golgi-Cox, Hippocampus, Cortex | scantox.com/wp-content/uploads/2024/10/126-70-SpineDensity-EN.pdf | Discovery | n/a | 126-70.SpineDensity-EN | 10/2024 | services | discovery | n-a | |
| Tau Seeding | Animal Models | Phosphorylation, Abeta, Amyloid-beta, Neurofibrillary tangles | scantox.com/wp-content/uploads/2024/03/126-12-TauSeeding-EN.pdf | Discovery | Alzheimer's disease | 126-12-TauSeeding-EN | 04/2024 | animal-models | discovery | alzheimers-disease | |
| TDP43 mouse | Animal Models | Neuronal loss, Spinal Cord, Thalamus, Neuroinflammation, Motor deficits, Anxiety, Emotional learning | scantox.com/wp-content/uploads/2024/03/126-44-ALSTDP43-EN.pdf | Discovery | Amyotrophic lateral sclerosis | 126-44-ALSTDP43-EN | 04/2024 | animal-models | discovery | amyotrophic-lateral-sclerosis | |
| TDP43-induced | Animal Models | Muscle weakness, Neuroinflammation, Learning, Motor deficits, Neuronal loss, Ubiquitination | scantox.com/wp-content/uploads/2024/03/126-45-ALSTDP43induced-EN.pdf | Discovery | Amyotrophic lateral sclerosis | 126-45-ALSTDP43induced-EN | 04/2024 | animal-models | discovery | amyotrophic-lateral-sclerosis | |
| THMT mouse | Animal Models | Learning, Memory, Morris water maze, Tau, Phosphorylation | scantox.com/wp-content/uploads/2024/03/126-50-ADTMHT-EN.pdf | Discovery | Alzheimer's disease | 126-50-ADTMHT-EN | 04/2024 | animal-models | discovery | alzheimers-disease | |
| Ulcerative Colitis | Animal Models | Sodium Sulphate, DSS, Body weight, Colon length, Colon Score | scantox.com/wp-content/uploads/2024/07/123-68-UlcerativeColitis-EN.pdf | Discovery | Other | 123-68-UlcerativeColitis-EN | 07/2024 | scantox.com/services/discovery/other/efficacy/colitis-models/ | animal-models | discovery | other |
| Vaccine Services | Services | Immunogenicity, Effect, Regulatory Toxicology, | scantox.com/wp-content/uploads/2024/07/123-66-VaccineServices-EN.pdf | Discovery | Other, SARS-CoV | 123-66-VaccineServices-EN | 07/2024 | scantox.com/services/discovery/other/infectious-diseases-and-vaccines/ | services | discovery | other sars-cov |
| Virus Injections | Services | BSL-2, BSL2, Intracerebral, Intraventricular, Intravenous, Mice, Rats, In vivo, In vitro | scantox.com/wp-content/uploads/2024/03/126-11-VirusInjections-EN.pdf | Discovery | n/a | 126-11-VirusInjections-EN | 04/2024 | services | discovery | n-a | |
| Wound Healing Models in Minipigs | Animal Models | Hair, Skin, Thickness, Dermis, Subdermis, Immunological response | scantox.com/wp-content/uploads/2024/04/122-62-WoundHealingModelsinMinipigs-EN.pdf | Discovery | Wound Healing | 122-62-WoundHealingMinipigs-EN | 10/2023 | scantox.com/services/discovery/other/wound-healing/ | animal-models | discovery | wound-healing |
| Xenograft Models | Animal Models | Tumor growth, Inoculation | scantox.com/wp-content/uploads/2024/04/122-63-Xenograft-EN.pdf | Discovery | Cancer | 122-63-Xenograft-EN | 09/2022 | animal-models | discovery | cancer | |
| zQ175 mouse | Animal Models | Huntingtin, Body weight, Motor deficits | scantox.com/wp-content/uploads/2024/03/126-34-HuntingtonsZQ175-EN.pdf | Discovery | Huntington's disease | 126-34-HuntingtonsZQ175-EN | 04/2024 | animal-models | discovery | huntingtons-disease |
In Vitro
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Scantox は、遺伝子改変および非遺伝子改変の細胞株、グリア細胞、初代ニワトリ、ラットの末梢神経系および中枢神経系ニューロン（異なる発生段階）や器官型脳スライスなどを含む、数々の標準化細胞培養システムを使った in vitro 研究サービスを提供しています。 ご要望に応じて、新しい評価系の開発・バリデーションも行います。
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In Vivo
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中枢神経系の創薬における CRO トップリーダーとして、Scantox は遺伝子改変動物を使ったサービスを提供しています。 当社は、遺伝子改変疾患モデルの生成、特性化、維持、およびそれらモデルの薬品試験プロジェクトへの適用において、20 年以上の豊富な経験を有しています。
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Ex Vivo
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Scantox の in vivo 評価系は十分に特性化され有効性が認められているため、中枢神経系の創薬を次のレベルに押し上げる上で有用なツールとなります。 当社の in vivo 評価系に由来する様々な検体を含む当社のバイオバンクのサンプル資料を使い、お客様の研究を喜んでお手伝いさせていただきます。脳細胞、脳脊髄液および血漿サンプルなど、様々な年齢層の遺伝子改変動物および非遺伝子改変動物の細胞をご利用いただけます。
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組織学サービス
Scantox は、組織サンプルの採取から、実験手順および実験結果すべてを含む研究レポートの納品に至るまで、様々な組織学サービスを提供しております。 当社のアプローチは、お客様特有のニーズに合わせてどのようなサービスもカスタマイズできる、一連の手順構築ブロックに基づいています。 当社のワークフローにおいて、どこでも開始点または終了点として選んでいただくことができます。
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バイオマーカー
Scantox は、様々な疾病の解析に対応する幅広い範囲の分子生物学的解析方法を提供しております。 ユニットは QPS Neuropharmacology で行われる in vitro および in vivo 研究に対応していますが、外部の前臨床試験や臨床試験からの通常のサンプル解析も同じ手法で行われています。in vitro および in vivo の前臨床サンプル、および臨床サンプルにおいて同じ解析方法を用いることにより、研究プロジェクトのトランスレーション的価値が高まります。
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